01 · Two capsulesOne serving a day
Two capsules make one serving. Swallow with a glass of water.
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Pro+ Urolithin Precursor Alternative Complex
A pomegranate-based precursor formula with Akkermansia, CoQ10, PQQ and spermidine. 120 plant-based capsules, a 60-day supply.
- 800 mg pomegranate
- 60-day supply
- Batch report available
- Made in the USA
What does it do?
- What it is
- Each two-capsule serving supplies an 800 mg liposomal pomegranate extract complex and 2 billion AFU of Akkermansia, plus a 120 mg CoQ10 complex and 40 mg each of PQQ and spermidine complexes.
- What it does
- It supplies pomegranate precursors that gut bacteria can convert into urolithins, with four other components in the same two capsules.
- How to take it
- Take two capsules daily, preferably with a meal and a glass of water, together or split through the day. One bottle lasts 60 days.
Free with your pack
Free with this choice
Batch lab report Ships in 1–3 business days
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
About Pro+ Urolithin Precursor
Pro+ Urolithin Precursor Alternative Complex combines pomegranate extract with Akkermansia, CoQ10, PQQ and spermidine. It supplies precursors that gut bacteria can convert into urolithins. Urolithin A itself is not an ingredient.
Each serving contains an 800 mg liposomal pomegranate extract complex, a 120 mg liposomal CoQ10 complex, 40 mg each of liposomal PQQ and spermidine complexes, and 2 billion AFU of Akkermansia. One bottle holds 120 capsules, enough for 60 days at two daily.
What to expect from this bottle What to expect
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A plant-derived starting point
Pomegranate supplies polyphenol precursors. How much urolithin you make depends on your own gut microbiome.
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Five components in one bottle
Pomegranate, Akkermansia, CoQ10, PQQ and spermidine in the same two-capsule serving.
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A 60-day supply
120 capsules at two daily, so one bottle covers 60 servings.
Full descriptionWhat is in each serving · Reading the label · How to take it · Limitations
What is in each serving
Pro+ Urolithin Precursor Alternative Complex is a five-component dietary supplement. Each two-capsule serving contains four sunflower phospholipid complexes: 800 mg of liposomal pomegranate extract, 120 mg of liposomal coenzyme Q10, 40 mg of liposomal spermidine and 40 mg of liposomal pyrroloquinoline quinone (PQQ). The serving also contains 2 billion AFU of Akkermansia muciniphila. There are 60 servings in a bottle of 120 capsules.
Reading the label
- 1,000 mg per serving on the bottle is the four complexes added together: 800 + 120 + 40 + 40 mg. Their labeled weights include the phospholipid complexes; they are not equivalent amounts of isolated active compounds or 1,000 mg of urolithin A.
- 60,000 mg total on the front is the 1,000 mg serving times 60 servings.
- Liposomal means pomegranate, CoQ10, PQQ and spermidine are listed as complexes with sunflower-derived phospholipids. Each milligram amount on the label is the weight of the whole complex.
- AFU, or active fluorescent units, is how the label counts Akkermansia. It is a different counting unit from CFU, so the numbers are not interchangeable.
How to take it
The only other ingredient listed is a plant-based hypromellose capsule. Take two capsules a day, preferably at a meal and with water; they can be taken together or split through the day.
Limitations
Pomegranate precursors depend on microbial conversion, and people differ in their ability to complete that pathway, so this formula does not guarantee conversion. Including Akkermansia has not been shown to make this formula overcome low urolithin production in an individual, or to turn a low converter into a high converter. A change in how you feel would not, by itself, confirm urolithin A production.
No study establishes a time to noticeable results for this finished formula; the 60-day bottle describes your supply, not a promised time to results. The PQQ and spermidine amounts describe complexes and should not be compared directly with study doses of isolated compounds, and human studies of other spermidine preparations do not establish an effect for this formula. The liposomal format describes the formulation; it does not establish how much better this product absorbs than another preparation. Ingredient studies and the batch report answer different questions; see the lab and research section for the details.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
The precursor route explained
Gut bacteria can turn pomegranate-derived precursors into urolithins. Ellagitannins first break down into ellagic acid, which certain microbes then metabolize.
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What you take
800 mg
A pomegranate starting point
Each serving provides an 800 mg liposomal pomegranate extract complex, bound to sunflower phospholipids. Pomegranate is the source of the precursors that gut bacteria can turn into urolithins.
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Why add Akkermansia?
2 billion AFU
A gut microbe in each serving
Akkermansia muciniphila is included alongside the plant precursor, at 2 billion AFU per serving. You get the microbe and the pomegranate in the same two capsules.
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What else is inside?
5 components
CoQ10, PQQ and spermidine too
The same serving includes a 120 mg CoQ10 complex and 40 mg each of PQQ and spermidine complexes. These are separate compounds with their own research, in one bottle instead of several.
Five components in two capsules
Four sunflower phospholipid complexes plus Akkermansia, with each amount listed on the Supplement Facts panel. All amounts below are per two-capsule serving.
800 MG PER SERVING · LIPOSOMAL
Pomegranate extract
Liposomal Pomegranate Extract (Pomegranate Extract/Phospholipid complex from Sunflower)
A pomegranate extract and phospholipid complex from sunflower, and the plant source of urolithin precursors. Its 800 mg labeled amount is the weight of the complex.
The complete labelSupplement Facts · serving size 2 capsules · 60 servings
- • Liposomal Pomegranate Extract (Sunflower Lecithin Phospholipid Complex)\n• Liposomal Coenzyme Q10 (Sunflower Lecithin Phospholipid Complex)\n• Liposomal Spermidine (Sunflower Lecithin Phospholipid Complex)\n• Liposomal Pyrroloquinoline Quinone / PQQ (Sunflower Lecithin Phospholipid Complex)\n• Akkermansia muciniphila\n• Vegetable Cellulose (capsule)
The four liposomal amounts include their sunflower phospholipid complexes. † Daily Value not established.
No proprietary blend
All five component amounts appear on the Supplement Facts panel.
Sunflower phospholipid complexes
Pomegranate, CoQ10, PQQ and spermidine are listed in this format. Akkermansia has its own AFU amount.
Made in the USA
Manufactured in the USA from foreign and domestic materials, 120 plant-based capsules per bottle.
When and how to take it
Take two capsules a day, preferably with a meal and a glass of water. Choose a routine that is easy to remember.
01 · Two capsules
02 · With a mealWith a regular meal
Take both together, or split the serving between meals, such as one at breakfast and one at dinner.
03 · ReorderOne bottle lasts 60 days
120 capsules at two daily. Check how much is left before deciding when to reorder.
When you start
Review the ingredients and your existing supplements first. Keep track of when you take the capsules and how well you tolerate them.
As you continue
Keep the same two capsules with a meal each day, and use your notes from the first weeks to judge how the routine suits you.
For adults
For adults aged 18 and over. Do not use if pregnant or nursing.
Medication and conditions
Consult a healthcare professional before use if you take medication or have a medical condition.
Other supplements
Review your full routine with a physician or pharmacist, especially if it already contains CoQ10, PQQ, spermidine or Akkermansia.
Batch testing and ingredient research
A batch report tells you about the tested sample. Published studies tell you what researchers observed with particular ingredients, doses and participants. The studies below did not test this finished formula. Read the research sources.
Two kinds of evidence
Lab reportResults for the named batch and the tests reported. Match the lot number to your bottle.
Published researchFindings from specific ingredient preparations. Different doses, forms and study populations limit what they tell us about this product.
456 mgpomegranate assay · per two capsules
Read the assay units alongside the label
The current report lists liposomal pomegranate extract at 456 mg per two capsules against a minimum specification of 420 mg, spermidine 3HCl at 21 mg against 20 mg, and PQQ at 22 mg against 20 mg. These assay entries are not the same as the whole phospholipid-complex weights printed on the label. The CoQ10 result is written as 69 "mg/capsules" against a minimum of 60 mg per two-capsule serving, so the report does not make its denominator clear.
Ask us to clarify the CoQ10 units
Qalitex COA-2026-9150003, Rev. 05, lot DK26-POM01-02About 40%of 100 adults · after 240 mL of juice
Urolithin production varies between people
In a randomized, open-label crossover study of 100 healthy adults, about 40% had blood urolithin A glucuronide above 100 ng/mL 24 hours after 240 mL of pomegranate juice; others had lower or undetectable levels. A separate 500 mg urolithin A intervention gave more consistent exposure. Amazentis funded the study, and several authors reported company ties. In a four-week randomized, double-blind pilot of 250 mg daily Pomella pomegranate extract with 18 completers, plasma urolithin A rose 6.6% versus 1.1% with placebo, a difference that was not statistically significant (p = 0.13). Neither study tested this complex or predicts an individual's conversion.
Singh et al., 2022; Sivamani et al., 2024300 mga day · 420 adults · two years
Study dose and population matter
The randomized, double-blind Q-SYMBIO trial studied 420 adults with a specific health condition, using 300 mg of CoQ10 daily for two years alongside standard care. That patient study does not establish an energy benefit in healthy adults taking this formula, and its dose differs from the 120 mg CoQ10 phospholipid complex listed here.
Mortensen et al., 201412 months100 older adults · 0.9 mg a day
The larger memory trial did not meet its main goal
SmartAge randomized 100 older adults with subjective cognitive decline to a wheat-germ supplement providing 0.9 mg of spermidine daily or placebo for 12 months. It did not significantly improve the primary memory outcome. The preparation and dose differ from this 40 mg liposomal complex, and the trial does not establish a memory benefit for Pro+ Urolithin Precursor.
Schwarz et al., 202220 mga day · 41 older adults · 12 weeks
Early findings from a small human trial
A randomized, double-blind, placebo-controlled study of 41 older healthy adults tested 20 mg daily of PQQ disodium salt for 12 weeks. It reported improvement on a selected attention measure; a visual-spatial result improved only in a subgroup with lower starting scores. This was a different preparation from the 40 mg PQQ phospholipid complex here, and the findings do not establish an overall cognitive benefit for this product.
Itoh et al., 201610 billionbacteria a day · 32 completers · 3 months
Preparations and counting units differ
A randomized, double-blind exploratory trial enrolled 40 overweight or obese volunteers; 32 completed three months. Researchers studied live or pasteurized Akkermansia preparations at 10 billion bacteria daily, compared with placebo, and assessed metabolic markers. That dose and preparation should not be treated as equivalent to this product's 2 billion AFU, and the trial does not show that this formula increases urolithin A production or reproduces the studied effects.
Depommier et al., 2019Current certificate of analysis
Research and batch report sources 7
- Qalitex Inc. Certificate of analysis COA-2026-9150003, Rev. 05. Lot DK26-POM01-02, batch N260903-004, released September 11, 2026. View the batch report ↗
- Singh A, et al. Direct supplementation with urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the population. European Journal of Clinical Nutrition. 2022;76(2):297-308. Read the study ↗
- Sivamani and colleagues. Four-week standardized pomegranate extract pilot. Foods, 2024. Read the study ↗
- Mortensen and colleagues. Q-SYMBIO randomized trial of coenzyme Q10, 2014. Read the study ↗
- Schwarz and colleagues. SmartAge randomized trial of spermidine, 2022. Read the study ↗
- Itoh and colleagues. PQQ disodium salt and cognitive function, 2016. Read the study ↗
- Depommier and colleagues. Exploratory human trial of Akkermansia muciniphila, Nature Medicine, 2019. Read the study ↗
What people ask before they start
No. It contains pomegranate extract complex, Akkermansia, CoQ10, PQQ and spermidine. Urolithin A is not listed as an ingredient. The bottle's 1,000 mg refers to the combined weight of the four liposomal complexes per serving.
This formula takes the precursor route: it supplies pomegranate compounds that gut bacteria can metabolize into urolithins. It is an alternative formulation, rather than an equivalent dose of urolithin A. That distinction matters if you are comparing products.
Conversion depends on your own gut bacteria, and we cannot predict it from how you feel. Akkermansia, CoQ10, PQQ and spermidine are in every serving either way. See what the human research measured before choosing a precursor approach.
Two capsules daily, preferably with a meal and a glass of water. Take them together or split them through the day, such as one at breakfast and one at dinner.
One bottle contains 120 capsules, or 60 two-capsule servings. At the suggested use of two capsules daily, it lasts 60 days.
There is no established time to a noticeable effect for this finished formula. The 60-day supply is a bottle count, not a results window.
Pomegranate, CoQ10, PQQ and spermidine are listed as complexes with sunflower-derived phospholipids. Each milligram amount is the weight of that complex, rather than the isolated active alone. Akkermansia is listed separately in AFU.
Have a physician or pharmacist review your complete supplement and medication list before combining them. Check for overlapping CoQ10, PQQ, spermidine or Akkermansia in other products too.
Do not use if you are under 18, pregnant or nursing, or allergic to an ingredient. Consult a healthcare professional before use, especially if you take medication or have a medical condition. If you develop an adverse reaction, stop taking it and seek professional advice.
Find Pro+ Urolithin Precursor Alternative Complex in our lab results directory and match the lot number to your bottle. The report summary above covers lot DK26-POM01-02, including its assay units. Contact our team if you need a report for another lot or clarification of an entry.
The standard policy allows eligible unused returns within 30 days, with conditions and sale-item exclusions. Qualifying 2- and 3-pack orders also carry a 90-day guarantee; the pack offer on this page shows when it applies. It permits one claim per customer. Other conditions and exclusions apply; the policy in force at purchase governs. Read the full refund policy and claim procedure.
Still have a question about the ingredients or your bottle's report?
Talk to our team
Make room for a daily routine
- 800 mg of pomegranate phospholipid complex and 2 billion AFU of Akkermansia per serving
- CoQ10, PQQ and spermidine complexes in the same two capsules
- 120 capsules, 60 days at two daily
Batch lab report available · Ships in 1–3 business days
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
For adults aged 18 and over. Do not use if pregnant or nursing. Consult a healthcare professional before using this or any dietary supplement, especially if you take medication or have a medical condition. Keep out of reach of children.