Rated 4.7 out of 5 stars

GHK-Cu Copper Peptide Face & Neck Serum

A concentrated copper peptide serum designed to support smoother-looking texture, visible firmness, hydration and fine-line care across the face, neck and décolletage.

1,200mg Copper Tripeptide-1 in a 4% GHK-Cu formula

Lightweight daily formula for the face, neck and décolletage

Formulated with niacinamide, aloe, glycerin and skin-conditioning oils

Best forFine lines, uneven-looking texture, dryness, dullness and loss of visible firmness

UseMorning or evening

TextureLightweight serum

Skin areasFace, neck and upper chest

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What Can GHK-Cu Serum Do for Your Skin?

Support Smoother-Looking Texture

Skin may begin to feel rougher or look less even as hydration levels, environmental exposure and normal aging affect its surface.

GHK-Cu and the serum's hydrating ingredients are designed to support a softer, smoother-looking complexion with regular use.

Soften the Appearance of Fine Lines

Fine lines often look more noticeable when skin is dry or poorly conditioned.

Copper peptides, glycerin, aloe vera and skin-conditioning oils work together to support a more supple appearance. The serum will not permanently remove wrinkles, but it may help fine lines look softer over time.

Support Firmer-Looking Skin

GHK-Cu is widely used in peptide skincare intended to support the appearance of skin firmness and elasticity.

Visible changes are gradual, so evaluate the serum over several weeks rather than judging it after only a few applications.

Improve the Look of Uneven Tone

Niacinamide and kojic acid complement the copper peptide by supporting a brighter and more even-looking complexion.

This is a cosmetic benefit and should not be confused with treatment for a medical pigmentation condition.

Provide Lightweight Hydration

Aloe vera and glycerin help attract and retain moisture at the skin's surface.

Jojoba oil, rice bran oil and vitamin E provide additional conditioning without turning the serum into a heavy face cream.

Extend Your Routine Beyond the Face

The neck and décolletage are often left out of daily skincare despite being regularly exposed to dryness and environmental stress.

This serum is designed for all three areas, making it easier to follow one consistent routine.

Description

A High-Strength GHK-Cu Serum for Daily Skin Care

GHK-Cu serum offers a peptide-focused way to support the visible signs of healthy skin aging without turning your routine into a long list of complicated steps.

GHK-Cu stands for glycyl-L-histidyl-L-lysine copper. In cosmetic ingredient lists, it is commonly identified as Copper Tripeptide-1. This small copper-binding peptide has been studied for its relationship with processes involved in skin structure, conditioning and appearance.

Neurogan Health GHK-Cu Copper Peptide Face & Neck Serum contains 1,200mg of Copper Tripeptide-1 in a concentrated 4% formula. It combines the peptide with niacinamide, aloe vera, glycerin, kojic acid, jojoba oil, vitamin E and rice bran oil.

The result is a lightweight serum designed to support smoother-looking texture, visible firmness, hydration and a more even-looking complexion with consistent use.

It is also made for more than the face. You can apply it to the neck and décolletage, where dryness, fine lines and visible changes in texture often become easier to notice.

This is not an overnight wrinkle treatment. GHK-Cu works best as part of a consistent routine that also includes gentle cleansing, moisturizer and daily sunscreen.

Ingredients

Copper Tripeptide-1 (GHK-Cu): the signature copper peptide; supports smoother, firmer-looking skin.
Aloe Barbadensis Juice: lightweight hydration; calms dry-feeling skin.
Vegetable Glycerin: a humectant that draws moisture to the surface.
Niacinamide: supports the barrier, hydration and a more even-looking tone.
Kojic Acid: supports brighter, more even-looking tone.
Jojoba, Papaya and Rice Bran Oils: condition and soften without heaviness.
Vitamin E (Tocopherol): antioxidant and conditioning support.
Phenoxyethanol & Ethylhexylglycerin: preservation and product stability.

Complete list: GHK-Cu (Copper Tripeptide-1), Aloe Barbadensis Juice, Guar Hydroxypropyltrimonium Chloride, Vegetable Glycerin, Kojic Acid, Carica Papaya Seed Oil, Simmondsia Chinensis Seed Oil, Ethylhexylglycerin, Phenoxyethanol, Tocopherol, Niacinamide, Oryza Sativa Bran Oil, Citrus Medica Limonum Peel Oil, Lemon Essential Oil, Distilled Water.

Transparency: This formula contains lemon peel oil and lemon essential oil. If you have very reactive skin or a known sensitivity to essential oils, patch test before full application.

Lab Results

Our GHK-Cu Copper Peptide Face & Neck Serum are third-party lab tested to ensure highest quality, purity, and safety.

GHK-Cu Copper Peptide Neck & Face Serum Lab Result

GHK-Cu Copper Peptide Neck & Face Serum Lab Result 1200mg 2026

WATCH IT IN YOUR ROUTINE

See how GHK-Cu Face & Neck Serum fits into your skincare routine.

Our 4% GHK-Cu Face & Neck Serum absorbs quickly without a heavy finish. See how easily it layers into a daily routine for the face, neck and décolletage, and why consistent use is key to supporting smoother-looking texture, visible firmness and hydration.

Week 1–3

Week 4–8

Week 9–12

Week 1–3

Most users first notice improvements in hydration, softness and overall skin comfort as skin adapts to the formula and moisturizing ingredients begin supporting the barrier.

✓ Formulated with Clinically Studied Ingredients

Carefully formulated with clinically studied ingredients and rigorously third-party tested for quality and consistency.

Week 4–8

With consistent daily use, many begin noticing smoother-looking texture and improvements in overall appearance. This is a good time to compare progress using photographs taken under the same lighting.

✓ Formulated with Clinically Studied Ingredients

Carefully formulated with clinically studied ingredients and rigorously third-party tested for quality and consistency.

Week 9–12

Longer-term use may support improvements in the appearance of fine lines and visible firmness. Individual results vary depending on age, sun exposure, skincare routine and overall skin condition.

✓ Formulated with Clinically Studied Ingredients

Carefully formulated with clinically studied ingredients and rigorously third-party tested for quality and consistency.

✓ Formulated with Clinically Studied Ingredients

Carefully formulated with clinically studied ingredients and rigorously third-party tested for quality and consistency.

Support Smoother-Looking Texture

GHK-Cu and the serum's hydrating ingredients are designed to support a softer, smoother-looking complexion with regular use.

4% High-Strength GHK-Cu Formula

Contains 1,200mg of Copper Tripeptide-1 in a concentrated formula designed for daily face, neck and décolletage care.

Supports the Appearance of Fine Lines

Copper peptides, glycerin, aloe vera and conditioning oils work together to support a smoother, more supple-looking appearance over time.

Lightweight Daily Serum

Designed to layer comfortably beneath moisturizer, sunscreen and makeup without the heaviness of a rich cream.

Supports a More Even-Looking Complexion

Niacinamide and kojic acid complement GHK-Cu by supporting brighter-looking, more even-looking skin.

Made for Face, Neck & Décolletage

One lightweight serum designed for the three areas where visible skin aging commonly appears.

The signature copper peptide that supports smoother-looking skin, visible firmness and overall skin quality. Concentrated at 1,200mg in a 4% formula designed for daily cosmetic use.

Niacinamide, aloe vera, glycerin, jojoba oil, papaya seed oil, rice bran oil, vitamin E and kojic acid help support hydration, skin comfort and a more even-looking complexion.

No artificial additives

No unnecessary fillers

No low-quality ingredients

No artificial colors or flavors

How We Compare

Feature	GHK-Cu Serum	Retinol
Main Goal	Support visible firmness, hydration and smoother-looking skin	Address photoaging, wrinkles and uneven tone
Typical Irritation	Usually lower, though irritation is still possible	Often higher, especially during adjustment
When to Apply	Morning or evening	Typically evening only
Suitable for Beginners	Often yes	Usually requires slower introduction
Main Strength	Peptide-focused skin support	Long clinical history for photoaging

FDA disclaimer

For external use only. Avoid direct contact with the eyes. Patch test before use. Discontinue use if persistent irritation occurs. Keep out of reach of children. This cosmetic product is not intended to diagnose, treat, cure or prevent any disease.

Customer Reviews

How to Use GHK-Cu Face and Neck Serum

Wooden spatula with blue face cream, showing product texture and directions for face and neck application.

Step 1

Cleanse & Prepare

Cleanse the face, neck and upper chest. Pat skin dry before applying the serum.

Step 2

Apply Evenly

Dispense a small amount onto clean fingertips. Spread a thin, even layer across the face, neck and décolletage. Allow it to absorb before applying moisturizer.

Step 3

Finish Your Routine

Apply moisturizer after the serum, and finish with broad-spectrum sunscreen during the day. Morning or evening both work; choose the routine you'll follow consistently.

The Science Behind GHK-Cu

GHK-Cu is a naturally occurring copper-binding peptide made of three amino acids, studied for decades for its relationship with skin maintenance and extracellular-matrix activity. Laboratory studies associate it with collagen-related proteins, skin remodeling and antioxidant responses, and cosmetic research reports improvements in the appearance of skin quality after topical use.

Ingredient research is not the same as finished-product performance, so no brand can promise identical results. Still, GHK-Cu remains one of the better-studied cosmetic peptides, best used as part of a complete skincare routine rather than a miracle ingredient.

01 Boosts Collagen and Elastin Production

GHK-Cu has been shown to increase collagen synthesis in fibroblast cultures and upregulate the expression of elastin and other structural proteins. It simultaneously suppresses MMP enzymes (which break down collagen) and increases TIMP expression (which protects it). The net effect: your skin builds more and loses less. [2]

02 Supports a Calmer, Healthier-Looking Complexion

03 Improves Overall Skin Quality

Who It's For

Who Is This GHK-Cu Serum For?

This is perfect for you if…

✓Want to support smoother-looking skin texture.

✓Are concerned about fine lines or reduced visible firmness.

✓Prefer a lightweight serum over a rich cream.

✓Want one product for the face, neck and décolletage.

✓Want a peptide-focused formula with niacinamide, aloe, glycerin and conditioning oils.

✓Value access to product-testing documentation.

This might not be for you if…

✕Expect overnight or guaranteed wrinkle removal.

✕Have a known sensitivity to essential oils or another listed ingredient.

✕Have broken, severely irritated or actively inflamed skin.

✕Need a rich moisturizer rather than a lightweight serum.

✕Are looking for an injectable or oral GHK-Cu product.

✕Prefer a completely fragrance-free formula.

What does GHK-Cu serum do?

GHK-Cu serum is used to support smoother-looking texture, visible firmness, hydration and the appearance of fine lines. Results depend on the formula, your skin and how consistently you use it.

Is GHK-Cu the same as Copper Tripeptide-1?

GHK-Cu is the copper complex of the tripeptide glycyl-L-histidyl-L-lysine. In cosmetic ingredient lists, it is commonly identified as Copper Tripeptide-1.

How often should I use this serum?

Begin once daily. People with sensitive skin may prefer every-other-day use during the first week before gradually increasing the frequency.

How much should I apply?

Apply a thin, even layer across the face, neck and décolletage. Follow the verified directions on the current product label for the recommended number of pumps.

Can I use GHK-Cu serum every day?

Yes, provided your skin tolerates the formula. Daily use is not necessary if your skin becomes dry or irritated. Every-other-day use may still fit a consistent routine.

Should I use GHK-Cu in the morning or at night?

You can use it in either routine. When applying it in the morning, follow with moisturizer and broad-spectrum sunscreen.

Can I use GHK-Cu serum twice a day?

Some users may tolerate morning and evening application, but twice-daily use is not automatically better. Begin once daily and increase only if the product directions and your skin tolerance support it.

Can I apply it under makeup?

Yes. Allow the serum to absorb, then apply moisturizer and sunscreen before makeup.

Can I use it on my neck and chest?

Yes. This product is designed for the face, neck and décolletage.

Can I use GHK-Cu with hyaluronic acid?

Yes. Hyaluronic acid primarily supports hydration and can generally be used in the same routine as copper peptides.

Can I use GHK-Cu with niacinamide?

Yes. Niacinamide is already included in this formula to support hydration, barrier function and a more even-looking complexion.

Can I use GHK-Cu with retinol?

Some people tolerate both products, but using them in separate routines may reduce irritation. Introduce them gradually and follow professional guidance when using a prescription retinoid.

Can I use GHK-Cu with vitamin C?

Compatibility depends on the vitamin C formula and your skin tolerance. Low-pH L-ascorbic acid products may be easier to use in a separate routine. Gentler vitamin C derivatives may be easier to layer.

Can I use GHK-Cu with exfoliating acids?

You may be able to use both, but strong alpha-hydroxy or beta-hydroxy acid products can increase irritation. Consider alternating routines instead of applying several strong actives together.

Does GHK-Cu serum remove wrinkles?

No topical cosmetic permanently removes wrinkles. GHK-Cu may help soften the appearance of fine lines by supporting hydration, conditioning and overall visible skin quality.

How long does GHK-Cu serum take to work?

Hydration or softness may become noticeable first. Changes in texture, fine lines or visible firmness may take eight to twelve weeks to assess. Individual results vary.

What happens if I stop using it?

There is no established withdrawal effect. Any cosmetic benefits supported by consistent use may gradually become less noticeable after the product is discontinued.

Is this serum suitable for sensitive skin?

Sensitivity varies. Patch test first and begin slowly. The formula contains lemon peel oil and lemon essential oil, which may not suit every reactive skin type.

How should I store the serum?

Keep it tightly closed in a cool, dry place away from direct sunlight and excessive heat. Follow the storage instructions printed on the current packaging.

Is this product fragrance-free?

No fragrance-free claim should be made while the formula contains lemon peel oil and lemon essential oil.

Where can I find the lab results?

Available testing documentation can be reviewed through the Neurogan Health lab-results page.

Are there any side effects or safety precautions?

GHK-Cu serum is for external cosmetic use, and irritation is possible (redness, stinging, itching, dryness, breakouts or localized sensitivity). Patch test before first use: apply a small amount to clean skin and wait at least 24 hours. Discontinue use if irritation persists or worsens, and seek medical care for severe reactions such as swelling or difficulty breathing. If you are pregnant, breastfeeding, using prescription skincare or treating an ongoing skin condition, consult a qualified healthcare professional before use.

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Try It Risk-Free

We're confident in the quality of our GHK-Cu Face & Neck Serum and back it with our satisfaction guarantee. If you're not satisfied with your purchase, contact our team within the applicable guarantee period and we'll help make it right.

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The Full Routine

Complete Your Routine

For the best cosmetic results, use GHK-Cu serum as one part of a complete skincare routine.

Gentle cleanser
GHK-Cu Copper Peptide Serum
Moisturizer
Broad-spectrum SPF 30+ every morning

Simple, consistent routines are generally easier to maintain than routines built around numerous active ingredients.

Ready when you are

Add GHK-Cu Serum to Your Daily Routine

Neurogan Health GHK-Cu Copper Peptide Face & Neck Serum combines a concentrated copper peptide formula with niacinamide, aloe, glycerin and skin-conditioning oils.

It is designed for adults who want to support smoother-looking texture, visible firmness, hydration and fine-line care without adding a heavy cream to their routine.

Use it consistently, keep your routine simple and give gradual cosmetic changes time to develop.

1,200mg Copper Tripeptide-1 per bottle
Lightweight face, neck and décolletage formula
Use morning or evening
One-time purchase and subscription options

Looking for other copper peptide formats? Explore all Neurogan Health GHK-Cu products.

References

[1] Pickart L, Margolina A. Regenerative and protective actions of the GHK-Cu peptide in the light of new gene data. International Journal of Molecular Sciences. 2018;19(7):1987.

[2] Pickart L, Vasquez-Soltero JM, Margolina A. GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration. BioMed Research International. 2015;2015:648108.

[3] Fife DJ, et al. Effects of topical copper tripeptide complex on carbon dioxide laser-resurfaced skin. Archives of Facial Plastic Surgery. 2006;8(4):252-259.

[4] Hostynek JJ, Dreher F, Maibach HI. Human skin penetration of a copper tripeptide in vitro as a function of skin layer. Inflammation Research. 2011;60(1):79-86.

[5] Mehta RC, Fitzpatrick RE. Skin rejuvenation using cosmetic products containing growth factors, cytokines and matrikines: a review of the literature. Journal of Drugs in Dermatology. 2007;6(6):654-662.

[6] Cosmetic Ingredient Review Expert Panel. Safety assessment of Tripeptide-1, Hexapeptide-12, their metal salts and fatty acyl derivatives, and Palmitoyl Tetrapeptide-7 as used in cosmetics.

[7] National Center for Biotechnology Information. PubChem compound information for Copper Tripeptide-1.

[8] U.S. Food and Drug Administration. Cosmetics safety and labeling guidance.

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GHK-Cu Copper Peptide Face & Neck Serum

GHK-Cu Copper Peptide Face & Neck Serum

What Can GHK-Cu Serum Do for Your Skin?

Support Smoother-Looking Texture

Soften the Appearance of Fine Lines

Support Firmer-Looking Skin

Improve the Look of Uneven Tone

Provide Lightweight Hydration

Extend Your Routine Beyond the Face

Description

A High-Strength GHK-Cu Serum for Daily Skin Care

Ingredients

Lab Results

Customer reviews

Real People. Real Results.

See how GHK-Cu Face & Neck Serum fits into your skincare routine.

When Can You Expect Results?

Week 1–3

Week 4–8

Week 9–12

Benefits Of Consistent Use

Support Smoother-Looking Texture

4% High-Strength GHK-Cu Formula

Supports the Appearance of Fine Lines

Lightweight Daily Serum

Supports a More Even-Looking Complexion

Made for Face, Neck & Décolletage

One Copper Peptide. A Complete Supporting Formula.

GHK-Cu (Copper Tripeptide-1)

Supporting Ingredients

How We Compare

Customer Reviews

How to Use GHK-Cu Face and Neck Serum

Cleanse & Prepare

Apply Evenly

Finish Your Routine

The Science Behind GHK-Cu

Who Is This GHK-Cu Serum For?

Try It Risk-Free

Complete Your Routine

Add GHK-Cu Serum to Your Daily Routine

Research-informed wellness for healthy aging.