What is a spermidine supplement used for?

Spermidine supplements are used to support cellular wellness and the natural process of cell renewal. Many people take them to fill gaps in their dietary intake of spermidine to support a healthier aging process.

Does spermidine have side effects?

Spermidine is generally well-tolerated when taken at the recommended dosages and isn't found to have any serious side effects. No supplement is without its potential risks, so it could be a good idea to consult a healthcare provider.

Is there a best time of day to take spermidine supplements?

Spermidine can be taken at any time of day, according to personal preference and convenience. The key to making the most of your spermidine-rich dietary supplements is to take them consistently.

Are there any interactions between spermidine supplements and medications?

There are no well-documented interactions. That being said, it's still important to consult with a healthcare provider before starting spermidine if you are taking other medications .

Can spermidine supplements replace other therapies or medications?

No, spermidine supplements are not intended to replace medical therapies or medications. Always follow the advice of your healthcare provider.

How long does it take to see the benefits of taking spermidine supplements?

As with many dietary supplements, results may vary. Spermidine is intended to support cellular health over time, and benefits may be observed with consistent use.

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Spermidine Supplements

Spermidine naturally occurs in the body as a key component of a cellular renewal process known as autophagy, which tends to slow down as we age. Supplements with spermidine will then recycle damaged cells and break them into newer & healthier cells.

Spermidine's Biological Role

Spermidine is a naturally occurring polyamine that has been studied for its role in the autophagy process. It’s also a precursor compound to other important polyamines, such as spermine and putrescin, which are linked to cellular growth, function, and adaptation.

Autophagy and Cellular Health

Research indicates endogenous spermidine induces autophagy by interacting with specific cellular pathways. For instance, spermidine may induce autophagy by inhibiting the acetyltransferase EP300, which leads to the acetylation of proteins involved in the autophagy mechanism [1]. In studies conducted in mice and flies, boosted spermidine levels were linked with extended cellular lifespan and improved cellular function through its influence on the autophagic process, which may influence cognitive function and the immune system [2,3].

Supplemental Benefits

Spermidine supplements are believed to enhance autophagy, the body's natural process of recycling damaged cells into new, healthy ones. As cellular waste accumulates with age, it can slow down cell function, leading to biological aging. Our high-quality spermidine trihydrochloride supplements are designed to support cellular renewal and function, offering a foundation for a long and healthy life starting at the cellular level.

Our Spermidine Source

Our spermidine is sourced through a biotechnological process for gluten-free semi-synthetic spermidine.

We use genetic engineering to enhance the natural abilities of specific microorganisms and cell cultures to produce spermidine efficiently.

The production involves fermentation in controlled environments, ensuring a high yield of spermidine. This method allows for more consistent concentrations of the compound and supports sustainable practices that are gentle on our environment.

Benefits of Pure Spermidine Supplements

While eating more spermidine-rich foods such as whole grains and mushrooms may help increase spermidine levels, these foods aren’t always a reliable source for a consistent daily dose, as the concentration of spermidine in foods can vary.

Potent and consistent doses

Gluten-free source

Support cellular health

How to Take Spermidine Supplements

Spermidine isn't fat-soluble, so it doesn't need to be taken with food to aid absorption. Doses typically start from 2-10 mg per day and can be increased up to 25 mg for a daily dose, according to your needs.

They can be taken at any time of the day, though some prefer taking them in the morning or before bed to align with the body’s natural rhythms of fasting and activity. The important thing with spermidine supplementation is consistent use as it helps the body use spermidine effectively over time, supporting the ongoing process of autophagy and cellular maintenance.

Unlike other spermidine brands, all our supplements come in three formats, all verified by third-party tests:

Tablets: Our spermidine tablets are quick to dissolve and easy to swallow, and they are a hassle-free way to take your daily dose.

Gummies: Delicious plant-based gummies containing a higher concentration of spermidine for enhanced support.

Droppers: Our tincture drops are best if you're looking for a more potent concentration of spermidine in a more customizable format.

"I started taking Neurogan Spermidine Supplement a little over a month ago. I have noticed a spike in my energy and some mental sharpness. My parents are approaching their seventies and while their energy is high we are considering adding this supplement to their regimen."

- Balencia C.

Frequently Asked Questions

The best type of spermidine depends on your personal preference for format (tablets, gummies, or drops) and your lifestyle needs. We've opted for isolated, high purity spermidine in our formulations over wheat germ extract spermidine to accommodate people's dietary needs for gluten-free options but also to have a more precise dosage of spermidine. Wheat germ extract can have varying spermidine levels depending on its growing conditions and processing.

Spermidine supplements are generally considered by individuals seeking to support their overall wellness, particularly focusing on cellular health, renewal processes, energy levels, and brain health.

Most commonly, adults of middle age or older might consider spermidine supplementation, as this is the life stage where natural cellular processes, including autophagy, may begin to decline. Supporting these processes can be part of a proactive approach to maintaining wellness as one ages.

While spermidine supplements can be started at any adult age, they do not replace a balanced diet or medical treatment.

There are no conclusive scientific studies to confirm that spermidine reverses grey hair or supports hair growth. Spermidine supplements are not intended to diagnose, treat, cure, or prevent disease or condition.

That being said, some people find that supporting their overall wellness with dietary supplements like spermidine and other lifestyle changes has led to indirect improvements in their hair, skin, and nails for a more youthful appearance.