GHK-Cu Copper Peptide Hair & Scalp Serum
$48
NMN + Resveratrol Capsules
$37
GHK-Cu Copper Peptide Face & Neck Serum
$44
Liposomal Vitamin C Capsules, 120 Count
$28
AHK-CU + GHK-CU Hair Serum Pro
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NMN Powder
$40
A measured 20 mg per dropper in a wild berry liquid: one in the morning, one at night.
Free with this choice
Batch lab report Ships in 1–3 business days
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Neurogan Health Spermidine Drops provide 20 mg of spermidine 3HCl in each 0.5 mL serving, in a wild berry liquid. Each 2 oz bottle holds 120 servings. Take two servings a day, one in the morning and one in the evening.
Each 0.5 mL dropper holds 20 mg of the spermidine 3HCl form listed on the Supplement Facts panel.
Take one dropper in the morning and one in the evening.
The current batch has a third-party certificate of analysis. You can open it in the Lab chapter below.
At two droppers a day, the 120 servings last about 60 days.
Adults who prefer a liquid and a measured, twice-daily routine.
Human studies of spermidine used other products, amounts and formulations, and results are mixed. Customer experiences vary.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Food and your own cells already supply some. A supplement adds a fixed daily amount.
In food
24 mg
Wheat germ is one of the richest sources, at about 24 mg per 100 g, followed by soybeans, aged cheese and mushrooms. How much you get depends on what you eat each day.
With age
Your cells make spermidine as well as taking it in from food, and levels in the body tend to decline as people get older.
In your cells
Spermidine is studied for its role in autophagy, the process cells use to break down and recycle worn components. The human studies so far are summarized in Lab & research.
Twice a day
40 mg
Two 0.5 mL droppers give 40 mg of spermidine 3HCl a day, the same amount whatever you eat. 3HCl names the salt form on the label; it is not a triple dose.
Food values are representative published measurements (Ali et al., 2011).
The three products differ in labeled amount, how many you take a day and how long a bottle lasts. Pick the one that fits your routine.
$20 a bottle
$0.33 a day · lasts about 60 days
Suits you if you prefer a liquid and are happy taking one dropper in the morning and one in the evening.
$24 a bottle
$0.40 a day · lasts about 60 days
Suits you if you want a tablet, one in the morning and one in the evening.
$34 a bottle
$0.28 a day · lasts about 120 days
Suits you if you want a once-daily 50 mg capsule and a bottle that lasts about 120 days.
90-day money-back guarantee on 2- and 3-packs · 30-day returns on unopened single bottles
No head-to-head study has compared these formats, so none has been shown to work better.
One dropper in the morning and one in the evening. Taking them at the same times every day makes the routine easy to keep.
01 · MorningTake one 0.5 mL dropper in the morning, on its own or in a glass of water. Pairing it with something you already do makes it easier to remember.
02 · Any mealYou can take the drops with or without food. Taking the morning dropper at breakfast ties it to a habit you already have.
03 · EveningTake the second dropper in the evening. At two droppers a day, a 60 mL bottle lasts about 60 days.
Set your two times and build the habit. Spermidine is not a stimulant, so there is nothing to feel right away.
Keep taking two droppers every day. Spermidine is meant for steady daily use over weeks, so consistency is what counts.
After about 60 days, look back on how the routine suits you. Subscribe and Save sends the next bottle so you do not break the streak.
If you combine spermidine with NMN, resveratrol or other supplements, or take medication, have your full routine reviewed by a healthcare professional.
Not for use by anyone under 18. Do not use if you are pregnant or nursing.
Consult a healthcare professional before using this or any dietary supplement, particularly if you take medication, are under medical care or are preparing for surgery.
One declared active ingredient in a wild berry liquid, listed as it appears on the product label.
DECLARED ACTIVE
Spermidine trihydrochloride
Spermidine 3HCl is spermidine in salt form, spermidine trihydrochloride, as listed on the Supplement Facts panel. It is a manufactured ingredient, not a wheat germ extract.
As listed on the Supplement Facts panel.
The amount of spermidine 3HCl is stated directly on the Supplement Facts panel.
The liquid also contains purified water, wild berry flavor and stevia sweetener. None of them is an active ingredient.
The active ingredient is spermidine 3HCl rather than a wheat-derived extract.
A lab report tests a specific product batch against defined specifications. Published research studies spermidine in different forms, doses, populations and settings. These are two different types of evidence, so we keep them clearly separated. Spermidine dosage guide
Two kinds of evidence
A 2026 double-blind, placebo-controlled pilot studied oral spermidine after a third SARS-CoV-2 vaccine dose. Researchers reported that supplementation was well tolerated and found increased autophagy-related gene activity in B cells, in line with higher autophagic flux. The study was small and specific to this setting.
Alsaleh et al., 2026A 2023 randomized crossover pharmacokinetic study found that oral spermidine increased plasma spermine but did not significantly increase plasma spermidine or putrescine. This suggests that orally consumed spermidine may be converted before appearing in systemic circulation. The study examined short-term metabolism, not clinical benefits.
Senekowitsch et al., 2023A randomized, double-blind, placebo-controlled study of a high-purity spermidine trihydrochloride found no significant changes in clinical, lipid, chemistry or blood measures, no product-related adverse events, and little change in circulating polyamines. It did not test 20 mg a day, women, long-term use or this product, and two authors worked for the ingredient’s maker.
Keohane et al., 2024The SmartAge trial tested a spermidine-rich wheat-germ extract in adults with subjective cognitive decline. It did not find a significant improvement in the primary memory endpoint or the main secondary outcomes compared with placebo. The tested form and amount were different from this product.
Schwarz et al., 2022Reviews marked Verified Buyer come from confirmed purchases.
Reviews describe individual experiences. They are not clinical evidence.
I noticed I always felt happier after taking this but I didn’t know if it was some placebo effect. This morning I woke up in the deepest depression. I had nothing to be depressed about but my period just started so I figured it was this. The day went by and I was spiraling more and more. I was about to end my relationship and all sorts of crazy things. Then I remembered I had spermidine. I took 0.5 mL and within 15 mins that crazy darkness lifted off of me. I was shocked. I’m never not having this around!
Tastes great and easier than pills. Plus super fast delivery.
++++
I look forward to taking this every morning after my broc shot. I feel really happy 10-15 mins after taking. I also used to get quite moody the week before my period and that hasn’t been as big of an issue for me since starting this.
I thought that drops would be a good idea, but they are very salty tasting to me, and I can hardly get them down. I'll take gummy delivery over these.
This has become my go to spermidine supplement. Since I take several capsule supplements, I really appreciate when I can get what I want in a great tasting liquid form. The bottle lasts a long time.
Since starting this product I have noticed an increase in daily energy and hair growth. Definitely recommend!
I love the Neurogan form of Spermadine. I use it every day. It is becoming more and more essential for anti aging and eye health!
Please don't listen to any reviews that speak of a bad flavor. It will put that in your mind as an expectation before you even try it. It almost has no taste except for a slight berry flavor.
Packaging looks great. I noticed taking it as far as my energy and mood while working out and throughout my day which is great to see some effects when you take a supplement. Sadly, how beneficial is anything and obviously this costs money. So while I may take it for a while to determine if I notice anything a month or two from now, I will have spent a nice sum just to see. The biggest dissapointment with this product is its very poor...I mean horrible dropper. I actually was contemplating buying another bottle and dropper just based on how bad this one is. When looking at value for money people want to see the value. I could honestly see this product failing just based on the dropper alone, which is sad. It could be a great product.
Individual results vary. These are customer experiences, not a clinical study.
Spermidine is a polyamine found in all living cells and is involved in important cellular renewal processes, while also exhibiting beneficial antioxidant properties.* It has been studied for its role in supporting normal cellular renewal and maintenance processes (autophagy) that help keep cells functioning efficiently as part of healthy aging.*
We recommend taking two servings of Neurogan Health Spermidine supplement drops daily, one in the morning and one in the evening. This will provide you with a daily dose of 40 mg that supports cellular function over time.
We recommend taking a spermidine supplement twice a day, once in the morning and again at night. Or if you choose only one timing, we recommend at night as it lines up with the body’s natural recovery process.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Not for use by persons under 18. Do not use if pregnant or nursing. Consult a healthcare professional before using this or any dietary supplement, especially if you take medication, are under medical care or are preparing for surgery.
