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Acne prone skin and popular peptide products. Text: The best copper peptides for acne in 2024

The Best Copper Peptides for Acne in 2024

Pimples, blackheads, and whiteheads can be the main of many people's worries — it's not just a teenage phase as skin concerns can follow you well into adulthood. The search for effective acne treatments has led researchers to explore various natural compounds, among which copper peptides, with their properties to support collagen and elastin production, serve as a promising solution.

In this article, we'll examine how copper peptides may be a valuable addition to your acne-prone skincare routine and the top-rated copper peptide products on the market.

Understanding Acne and its Causes

Acne is caused by the interplay of four main factors: excess oil production, clogged hair follicles by oil and dead skin cells, bacteria (specifically, Propionibacterium acnes), and inflammation.

Hormonal changes, diet, stress, and certain medications can exacerbate these factors, leading to the development and persistence of acne.

The Benefits of Copper Peptides: A Primer

Copper peptides are small protein fragments (amino) with a high affinity for copper ions (Cu+). They've been extensively researched for their wound healing, anti-inflammatory, and antioxidant properties that lend to their potential skin regeneration, hair growth, and anti-aging benefits.

How Copper Peptides Benefit Acne Prone Skin

Copper peptides work on acne-affected skin through several mechanisms. Their anti-inflammatory properties help reduce the redness and swelling associated with acne lesions.

Enhancing collagen production is believed to help heal acne scars, making them less visible over time. On top of this, copper peptides have been found to possess antimicrobial properties that may help control the population of P.acnes bacteria on the skin, thereby reducing the incidence of breakouts [1].

The Connections Between Copper and Women's Skin Health

Research suggests that hormonal fluctuations, especially those related to the menstrual cycle, can affect copper levels in the body. These fluctuations may influence the severity of acne in women.

This is why supplementing skincare routines with active copper peptides could potentially help in balancing these variations, offering a gentle approach to managing hormonal acne and irritated skin.

Top Copper Peptide Products for Acne Treatment

When selecting copper peptide products for acne treatment, it's essential to consider the entire ingredient list. Look for non-comedogenic items, which means they're formulated not to clog pores—a critical factor for acne-prone skin.

The optimal concentration of copper peptides is also key; we recommend a 4% concentration for daily use without irritation. Additionally, incorporating ingredients like vitamin C, retinol, and gentle exfoliants can further support acne-prone skin by promoting rejuvenation and reducing scars. This holistic approach ensures that you're not just focusing on one aspect of skin care but addressing acne management comprehensively.

With that out of the way, here are our top picks for copper peptide serums for acne scars and active acne.

  1. Neurogan Copper Peptide 4% Face and Neck Serum
  2. The Ordinary "The Buffet" Multi-Peptide + 1% Copper Peptide Serum
  3. Paula's Choice Multi Peptide Booster
  4. Neurogan Copper Peptide 4% Face Cream
  5. CosRX 6 Peptide Skin Booster

Neurogan Copper Peptide 4% Face and Neck Serum 

Bottle of Neurogan Copper Peptide 4% Face and Neck Serum

With a precise 4% concentration of Copper Tripeptide-1, this serum strikes an optimal balance between efficacy and gentleness, making it suitable for daily use.

Copper Tripeptide-1 is renowned for its skin rejuvenation properties, supporting the skin's natural healing processes. This serum aims to assist in the appearance of smoother, healthier skin without the harshness often associated with acne treatments. Additionally, this serum is enriched with niacinamide, a powerhouse ingredient known to support acne-prone skin by helping to improve the skin’s barrier function and reduce the appearance of skin blemishes.

Its formulation is designed to complement your existing skincare routine, potentially aiding in reducing the visibility of acne scars and promoting a more even skin tone.

  • Price: $21
  • GHK-Cu Concentration: 4%
  • Bottle Size: 1 oz (30 ml)
  • When to use: Day and Night

The Ordinary "The Buffet" Serum

Bottle of The Ordinary "The Buffet" Serum

While The Ordinary's serum is generally marketed for its anti-aging properties, its ingredient list also makes it a supportive ally in acne management.

"The Buffet" is not just about Copper Tripeptide-1; it's a rich concoction of peptides, including Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, and several others, complemented by Sodium Hyaluronate for hydration. This unique blend supports the skin's natural healing process, reducing dynamic lines and the appearance of acne scars. Including Lactococcus Ferment Lysate, a probiotic ingredient, further supports skin health.

Users appreciate its dual action in addressing signs of aging and promoting a clearer, more even-toned complexion and brighter skin.

This makes "The Buffet" Multi-Peptide + 1% Copper Peptide Serum a multi-tasking addition to any skincare regimen, offering anti-aging and acne-supportive benefits.

  • Price: $32
  • GHK-Cu Concentration: 1%
  • Bottle Size: 1 oz (30 ml)
  • When to use: Day and Night

Paula's Choice Multi Peptide Booster

Bottle of Paula's Choice Multi Peptide Booster

Paula's Choice Multi Peptide Booster is a sophisticated serum with additional amino acids designed to combat fine lines and wrinkles, yet its formulation offers significant benefits for those with acne-prone skin. This lightweight, silky gel formula is infused with six pro-collagen peptides. It provides multi-layer firming support that aims to rebuild and strengthen the skin deeper and teaches the skin how to maintain its youthful elasticity over time.

We will say that this isn't an affordable product for most people at $58 for less than 1 oz bottle. And it's ingredient list is geared towards anti-aging more than addressing acne directly. Still, the ingredients suggest it will support soothing irritated skin and promote healthy skin texture.

  • Price: $58
  • GHK-Cu Concentration: Not Disclosed
  • Bottle Size: 0.67 oz (20 ml)
  • When to use: Day and Night

Neurogan Health 4% Face and Neck Cream

Jar of Neurogan Health 4% Face and Neck Cream

Our Neurogan Health's 4% Copper Peptide Face Cream was formulated for those with dry, combination, and acne-prone, aging skin types. However, it fits anyone seeking a healthier glow to their complexion.

This cream has a lightweight, non-greasy texture that absorbs quickly, helping to moisturize without clogging pores or leaving any residue behind.

A blend of nurturing oils complements his potent ingredient — Olea Europaea (Olive) Fruit Oil, Passiflora Edulis (Passion Fruit) Seed Oil, Oryza Sativa (Rice) Bran Oil, and Euterpe Oleracea (Açaí Palm) Fruit Oil — each carefully selected for their hydrating and skin-softening properties.

Including Calendula Officinalis Flower Oil further enriches the formula, offering soothing benefits to calm irritated skin and promote a more even skin tone.

Neurogan Health's 4% Copper Peptide Face Cream is not just an alternative for those who prefer creams over serums; it's a straightforward addition to most skincare routines, offering ease of integration with its gentle yet effective formulation.

  • Price: $20
  • GHK-Cu Concentration: 4%
  • Bottle Size: 2 oz (60 mL)
  • When to use: Day and Night

CosRX 6 Peptide Skin Booster

Bottle of CosRX 6 Peptide Skin Booster

The CosRX 6 Peptide Skin Booster is another great skincare product formulated to address a spectrum of skin concerns, including dryness, wrinkles, brightness, acne, and hydration.

This versatile booster is a powerhouse that blends six targeted peptides and hyaluronic acid. It makes it an exceptional choice for enhancing the skin's barrier, providing wrinkle care, and brightening the complexion.

Understanding that oily skin isn't the sole cause of acne, the CosRX 6 Peptide Skin Booster recognizes that sometimes, overly dry skin can lead to increased sebum production, contributing to acne, or can cause surface dryness that clogs pores. To combat this, the booster includes hyaluronic acid and N-Acetyl Glucosamine (NAG), along with amino acids, to deeply hydrate and support the skin's natural moisture barrier, reducing the likelihood of both dryness-induced acne and clogged pores.

  • Price: $25
  • GHK-Cu Concentration: Not Disclosed
  • Bottle Size: 5.07 oz (150 mL)
  • When to use: Day and Night

Do Copper Peptides Work for Acne?

While the direct effect of copper peptides on acne bacteria (Propionibacterium acnes) and sebum production is unclear, their indirect benefits through anti-inflammatory action and skin repair mechanisms provide a compelling case for their inclusion in acne treatment regimens.

Copper peptides are known for their ability to soothe inflammation, a significant benefit for acne-prone skin, as acne is fundamentally an inflammatory condition. By mitigating inflammation, copper peptides can help reduce the severity of acne breakouts, lessen skin redness, and contribute to a calmer, more balanced skin appearance.

Copper Peptide Creams

Copper peptide creams are an excellent choice for those looking to simplify their skincare routines without compromising effectiveness. Their multifunctional nature means you can enjoy multiple benefits from a single product.

Applying a copper peptide cream after washing your face can provide the hydration, nourishment, and treatment needed to manage acne-prone skin effectively.

Topical creams containing copper peptides present a non-invasive option for acne treatment. Copper peptide creams offer a gentler approach, unlike more aggressive treatments that may irritate or dry out the skin. They are known for reducing inflammation—a key factor in acne development—thereby alleviating the redness and swelling associated with acne breakouts.

Copper Peptide Serums

The molecular composition of serums allows them to penetrate deeper into the skin compared to traditional creams.

Copper peptide serums take full advantage of this property, delivering anti-inflammatory and healing agents directly to the areas where they are most needed. This deep penetration ensures that the active ingredients effectively reduce inflammation, a key contributor to acne, and promote the healing existing acne lesions.

One of the advantages of serums is their compatibility with other skincare products. Copper peptide serums can be seamlessly incorporated into your skincare routine as a foundation for other products.

Their fast-absorbing nature ensures that they don't interfere with the application or effectiveness of subsequent products, such as moisturizers or sunscreens. This makes copper peptide serums an excellent choice for those who wish to layer multiple skincare products for a comprehensive approach to acne management.

Copper Peptide Injectable Solutions

While less common, injectable forms of copper peptides exist and are used in professional settings to target severe acne scars by stimulating deep tissue repair.

The effects can be significantly enhanced when copper peptide injectable solutions are combined with microneedling. The micro-injuries created by microneedling allow for deeper penetration of the copper peptides into the skin, where they can exert a more potent effect on the underlying tissue. This synergy accelerates the repair of acne scars and improves overall skin texture and firmness.

While you might be able to purchase microneedling devices to use at home, we highly recommend you visit an accredited skin clinic for these procedures to minimize the risk of injury and infection.

The Takeaway: Copper Peptides for Acne

For those interested in exploring the benefits of copper peptides for acne treatment, we invite you to visit our website, Neurogan Health. Here, you'll find a curated selection of copper peptide products designed to support skin health and address acne concerns, including creams, serums, and more. Our formulations are crafted with care, ensuring an optimal balance of efficacy and gentleness to cater to your skin's unique needs.

Adding copper peptides into your skincare regimen can be a transformative step towards achieving your desired radiant, acne-free complexion. With the right products and a commitment to consistent care, the path to improved skin health is within reach. Visit Neurogan Health today to discover how our copper peptide solutions can enhance your skincare journey.


  1. Pickart, L., & Margolina, A. (2018). Skin regenerative and anti-cancer actions of copper peptides. Cosmetics, 5(2), 29.
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Katrina Lubiano

Based in Canada, Katrina is an experienced content writer and editor specializing in health and wellness. With a journalistic approach, she's crafted over 900,000 words on supplements, striving to debunk myths and foster a holistic approach to healthi...