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The Ultimate Guide to The Best Brain Supplements

The Ultimate Guide to The Best Brain Supplements

If you feel like your brain is constantly running on low battery, it may be time to take action.

A number of factors can contribute to brain fog, like stress, a poor diet, lack of sleep, and other environmental factors.

The good news is that by taking care of your health holistically and incorporating some dietary supplements, you may be able to give your brain the boost it needs to function at its best.

In this article, we'll introduce the best brain supplements and dive into how they may support mental clarity and cognitive abilities.

Key Takeaways: Brain-Enhancement Supplements

  • Brain health supplements support cognitive function, improve memory, and boost mental clarity and focus.

  • Omega-3 fatty acids, B vitamins, antioxidants, and adaptogens are some of the most popular ingredients found in a brain supplement.

  • When shopping for dietary supplements, looking for high-quality, reputable brands that use safe and effective ingredients is important.

  • To maximize the benefits of brain boosters, it's important to follow a healthy diet, get regular exercise, and engage in activities that stimulate the brain.

  • While brain health supplements can be a helpful tool for supporting cognitive function, they should not be relied upon as a substitute for a healthy lifestyle or medical treatment if needed.

Types Of Brain Health Supplements

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The brain is the most complex organ in the body, responsible for our ability to think, reason, and feel. It's made up of billions of neurons that communicate with each other through electrical and chemical signals.

Keeping the brain active through activities like learning, problem-solving, and socializing is important to maintain cognitive function and prevent age-related cognitive decline. Brain supplements can also support brain health by providing essential nutrients and promoting healthy brain function. We can keep our brains healthy and functioning at their best with the right approach.

Whether you're a student looking to sharpen your brain power or an older adult looking to slow cognitive decline, finding the best brain supplements may help you to achieve your goals and feel your best.

Brain health supplements can come in various forms, such as omega-3 fatty acids, adaptogenic herbs, nootropics, flavonoids, and vitamins and minerals.

These supplements work in different ways to support brain function and can provide benefits such as improved memory, focus, and mood.

There is speculation among experts that actively supporting healthy brain function can potentially prevent cognitive decline and preserve mental acuity with age.

Let's take a look at the most common categories of brain health supplements and how they work.

1. Omega-3 Fatty Acids

Omega-3s are found naturally in fatty fish, nuts, and seeds but are popularly taken as a dietary supplement for consistent, high concentrations of this brain health supplement.

In fact, omega-3 fatty acids are one of the most studied dietary supplements, shown to support brain development in children, support cognitive function and memory recall in adults, and protect the brain against oxidative stress [1, 2].

The Best Type of Omega-3 fatty acids for mental performance

EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are the two most beneficial types of omega-3s found in cold-water fish (sardines, salmon, and mackerel).

When shopping for a high-quality omega-3 for overall brain health, make sure that the supplement is from a reputable source with third-party lab testing to verify its purity and potency.

2. B Vitamins

B vitamins, such as B6, B9 (folate), and B12, are important for brain health and function.

They help regulate neurotransmitters' production and promote brain cell growth and repair [3]. B vitamins can be found in leafy greens, whole grains, and fortified cereals and can also be taken as supplements for more concentrated doses to support certain wellness goals.

Shopping for B-Vitamins for long-term brain health

Look for supplements that include vitamins B6, B9, and B12, as these have been the most extensively researched in their potential to support brain functions.

You want to choose supplements that have these forms of B vitamins in their active form, such as methylcobalamin for B12 and pyridoxal-5-phosphate for B6, as these forms of vitamin B are much more bioavailable (easily absorbed).

You may also find some B vitamin supplements enhanced with other ingredients, such as adaptogens like ginkgo biloba and other brain-boosting compounds, which may have more targeted effects toward your goals.

3. Antioxidants

Antioxidants like vitamins C and E, resveratrol, and flavinoids may help support mental performance and maintain brain health as we age. You can find antioxidants naturally concentrated in colorful fruits, vegetables, nuts, and seeds.

The way antioxidants work is in its name.

They help to protect the brain from oxidative stress and inflammation, which is detrimental to brain health [4].

Choosing antioxidant supplements to support cognitive health

Antioxidants can come from many sources.

Whenever possible, choose an antioxidant dietary supplement that comes from natural sources over synthetic vitamins, and check the recommended daily intake for each nutrient to ensure you're getting the most of the antioxidant's potential for supporting cognitive abilities.

4. Adaptogens

Chronic stress and anxiety will take a toll on your brain power over time.

Adaptogens are herbal supplements that help the body cope with stress, supporting cognitive ability and promoting overall health and well-being [5].

The effectiveness of adaptogens for supporting optimal brain function will depend on the individual and the specific adaptogenic herb. For instance, in some studies, ashwagandha has been observed to boost brain power and memory recall, but in other studies, it didn't show the same effects [6, 7].

Choosing adaptogenic supplements for mental clarity and overall brain function

Some of the most popular adaptogenic herbs for brain health include Rhodiola rosea, Schisandra berry, ginkgo biloba, and holy basil.

Different types of adaptogens have different properties, so it's important to consider your specific wellness goals to help you narrow down the adaptogenic supplement that aligns with your lifestyle.

When shopping, check the supplement source to ensure it's free from fillers, additives, and potentially harmful substances, and carefully follow dosing instructions and gauge how your body responds to the compounds.

5. Nootropics

Nootropics are a class of dietary supplements and drugs that are designed to enhance cognitive function and promote brain health by modulating various neurotransmitters and other chemicals in the brain.

Some nootropics have been found to enhance blood flow, reduce inflammation, protect brain cells, and improve brain plasticity.

But not all nootropics are equal—some may have more research-backed benefits than others.

Looking for The best nootropics for cognitive performance

Several nootropics have been studied for their potential to improve cognitive performance.

Some of the most common nootropics include racetams, such as piracetam and aniracetam, which are believed to enhance memory and learning ability.

It's important to remember that not all nootropics are well-studied, and there's a chance that many of the nootropic supplements on the market aren't made to a high standard.

Look for products that third-party laboratories have tested for purity and potency. Read the labels carefully to ensure that the supplement contains the specific nootropic ingredients you are looking for, and check the dosage and recommended usage instructions.

Finally, consider consulting with a healthcare professional or a licensed nutritionist to ensure that the nootropics brain boosters you choose are safe and effective for your personal needs.

The Best Brain Supplements At Neurogan Health

Neurogan Health understands the importance of brain health and offers a variety of brain supplements to support your cognitive function, including memory, focus, and mood.

Our supplements are carefully formulated with natural ingredients that have been shown to support brain health, and we strive to provide the highest quality products to our customers.

1. Fisetin

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Fisetin is a flavonoid, a type of antioxidant, found in a variety of fruits and vegetables.

Studies conducted on animals have shown that fisetin may have the potential to improve memory by strengthening the connections between brain cells [8].

Our fisetin supplement stands out a cut above the rest for its premium sourcing and high bioavailability. With a potency of 500 mg per capsule, our fisetin supplement is designed to provide the utmost value and effectiveness our customers have come to rely on us for.

2. Spermidine

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Spermidine is a dietary supplement derived from wheat germ for a plant-based source.

It's a relatively newer supplement on the scene, but it's quickly gaining attention in wellness spaces for longevity and cognitive performance [9].

Our spermidine supplement delivers 10 mg of spermidine trihydrochloride in each fast-dissolving table to support brain and gut health.

3. Apigenin

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Apigenin is touted as a "brain-boosting flavonoid powerhouse" derived from herbs like chamomile and parsley.

While research on apigenin is still fairly new, some studies point to its potential for supporting the formation of brain cells and strengthening the connections between them, which may help to improve overall brain function [10].

At Neurogan Health, we take quality very seriously when it comes to producing our brain health and lifestyle supplements.

Our products are made with the highest quality ingredients and are manufactured in FDA-registered facilities that follow Good Manufacturing Practices (GMP).

We also conduct third-party testing on all of our products to ensure purity, potency, and consistency.

Our team of experts carefully monitors every step of the production process to guarantee that our customers receive safe, reliable, and effective supplements. We are committed to providing the best products possible to support brain health and overall wellness.

Frequently Asked Questions About The Best Brain Supplements

1. What are brain supplements, and how do they work?

Brain supplements, also known as cognitive enhancers, are dietary supplements researched and formulated to support optimal brain function.

Many different types of ingredients can be used in a cutting-edge brain supplement, including vitamins, herbs, amino acids, and other compounds. And different ingredients can work in a variety of ways—some improve blood flow to the brain, while others increase the production of neurotransmitters or protect against oxidative stress.

Overall, the point of taking brain health supplements is to support mental clarity, memory retention, and overall brain health.

2. Are brain supplements safe to take?

As long as you're taking high-quality brain-boosting supplements from a reliable source and according to the instructions, brain health supplements are generally safe for most people.

However, it's important that you consult with a healthcare professional if you're taking any long-term health supplement, are on medications, have an underlying health condition, or are breastfeeding or pregnant.

3. How long does it take for brain supplements to work?

The time it takes for brain supplements to work can vary depending on several factors, such as the specific supplement being taken, the dosage, and the individual's unique physiology. Some supplements, such as caffeine or other stimulants, may immediately affect cognition, while others may take longer to build up in the body and produce noticeable results.

It's important to follow recommended dosages and give supplements enough time to take effect, as some may take weeks or even months to produce significant changes in brain function. Additionally, lifestyle factors such as diet, exercise, and sleep can also impact the effectiveness of brain supplements.

4. Can I take multiple brain supplements at once?

Some brain supplements may complement each other and can be taken together, while others may interact negatively or have overlapping effects that could cause harm. It is always best to consult with a healthcare professional before taking multiple supplements at once to ensure they are safe and effective for you.

5. Are there potential side effects of brain supplements?

Yes, like with any supplement or medication, there is always the potential for side effects with brain supplements. The specific side effects depend on the ingredients and dosages of the supplements.

It's important to follow the recommended dosage and consult with a healthcare professional before adding any new supplements to your routine, especially if you have any underlying medical conditions or are taking other medications. Some common side effects of certain supplements include digestive discomfort, headaches, and changes in blood pressure.

The Takeaway: The Best Brain Supplements For Brain Fog

While taking care of your brain health with different supplements can be exciting and fun, brain health supplements should not be considered a healthy diet or lifestyle substitute.

A well-balanced diet rich in nutrients, regular exercise, adequate sleep, and stress management are all key factors in maintaining optimal brain health.

Whether you prefer the energizing effects of adaptogens or the cognitive boost of nootropics, there's a brain supplement out there for everyone.

Don't forget to research, look for high-quality ingredients, and consult your healthcare provider before adding new supplements to your routine.

With the right brain supplements and a positive attitude, you'll be ready to take on any mental challenge that comes your way.


  1. Innis, S. M. (2008). Dietary omega 3 fatty acids and the developing brain. Brain research, 1237, 35-43.

  2. Kuelzow, N., Witte, A. V., Kerti, L., Grittner, U., Schuchardt, J. P., Hahn, A., & Floeel, A. (2016). Impact of omega-3 fatty acid supplementation on memory functions in healthy older adults. Journal of Alzheimer's Disease, 51(3), 713-725.

  3. Huang, S. K., Lu, C. W., Lin, T. Y., & Wang, S. J. (2022). Neuroprotective role of the B vitamins in the modulation of the central glutamatergic neurotransmission. CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS & Neurological Disorders), 21(4), 292-301.

  4. Lee, K. H., Cha, M., & Lee, B. H. (2020). Neuroprotective effect of antioxidants in the brain. International journal of molecular sciences, 21(19), 7152.

  5. Panossian, A., & Wikman, G. (2010). Effects of adaptogens on the central nervous system and the molecular mechanisms associated with their stress—protective activity. Pharmaceuticals, 3(1), 188-224.

  6. Gopukumar, K., Thanawala, S., Somepalli, V., Rao, T. S., Thamatam, V. B., & Chauhan, S. (2021). Efficacy and safety of ashwagandha root extract on cognitive functions in healthy, stressed adults: a randomized, double-blind, placebo-controlled study. Evidence-Based Complementary and Alternative Medicine, 2021.

  7. Lopresti, A. L., Drummond, P. D., & Smith, S. J. (2019). A randomized, double-blind, placebo-controlled, crossover study examining the hormonal and vitality effects of ashwagandha (Withania somnifera) in aging, overweight males. American Journal of Men's Health, 13(2), 1557988319835985.

  8. He, W. B., Abe, K., & Akaishi, T. (2018). Oral administration of fisetin promotes the induction of hippocampal long-term potentiation in vivo. Journal of pharmacological sciences, 136(1), 42-45.

  9. Schroeder, S., Hofer, S. J., Zimmermann, A., Pechlaner, R., Dammbrueck, C., Pendl, T., ... & Madeo, F. (2021). Dietary spermidine improves cognitive function. Cell reports, 35(2), 108985.

  10. Salehi, B., Venditti, A., Sharifi-Rad, M., Kręgiel, D., Sharifi-Rad, J., Durazzo, A., ... & Martins, N. (2019). The therapeutic potential of apigenin. International journal of molecular sciences, 20(6), 1305.


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Katrina Lubiano

Based in Canada, Katrina is an experienced content writer and editor specializing in health and wellness. With a journalistic approach, she's crafted over 900,000 words on supplements, striving to debunk myths and foster a holistic approach to healthi...

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