01 · One pumpDispense onto your fingertips
Remove the clear cap and press the pump once. One pump is enough for the whole face.
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About this peptide cream
Syn-Ake Peptide Face Cream is a daily face cream built around Syn-Ake, a lab-made peptide used in skin care for the look of lines that come from movement: forehead lines, the lines between the brows and the outer eye area.
Each 1.69 fl oz (50 mL) airless pump holds 1,000 mg of Syn-Ake with copper peptide (GHK-Cu), plus NMN, L-glutathione and panthenol, in a base of olive, rice bran, passion fruit and acai oils. An independent lab measured all five actives in the current lot.
What it is designed to do Designed to
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A rich cream that absorbs without grease and layers under SPF
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Made to support softer-looking expression lines with twice-daily use
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Five actives, each measured per bottle on a published lab report
Full descriptionWhat is in the bottle · Reading the label · Who it suits · Limitations
Syn-Ake Peptide Face Cream is a cosmetic face cream for the look of expression lines. It pairs 1,000 mg of Syn-Ake peptide per 1.69 fl oz (50 mL) bottle with copper peptide (GHK-Cu), NMN, L-glutathione and panthenol, in an airless pump.
What is in the bottle
- Syn-Ake (dipeptide diaminobutyroyl benzylamide diacetate): 1,000 mg per bottle, measured at 1,008 mg
- GHK-Cu (copper tripeptide-1): measured at 310 mg per bottle
- Panthenol: measured at 514 mg per bottle
- L-glutathione: measured at 202 mg per bottle
- NMN (nicotinamide mononucleotide): measured at 52 mg per bottle
- Olive, calendula, passion fruit, rice bran and acai oils
Reading the label
- Amounts are per bottle, not per pump. They come from the certificate of analysis for lot DK26-SYF50-01 (Qalitex, Rev. 03, October 6, 2026).
- Syn-Ake is lab-made. It is a synthetic peptide modeled on a peptide first found in temple viper venom. Nothing in the cream comes from a snake.
- "Wrinkle-relaxing" on the bottle describes the look the cream is made for. It is a cosmetic and does not work like an injection.
- Cetyl alcohol is a fatty alcohol that thickens the cream, not a drying alcohol.
Who it suits
Adults who notice lines from expression on the forehead, between the brows or around the outer eyes, and want a peptide cream with measured amounts on a published lab report.
Limitations
This is a cosmetic, not a medical treatment, and it does not replace in-office procedures. Supplier tests of Syn-Ake used a 4% trade ingredient over 4 weeks, and the Neurogan evidence map rates the research as very preliminary. NMN and glutathione are studied mainly when taken by mouth. Results vary.
Made for the lines that come from movement
Where to smooth it on, and how much to use.
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01
Forehead lines, the lines between the brows and the creases at the outer eyes form where your face moves most.
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02
One pump covers the face. Smooth it over those areas first, then spread what is left.
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03
Use it morning and evening, and give it about four weeks before you judge the look of your lines.
Two peptides in a rich oil base
There are 19 ingredients on the label. These cards cover the actives and the oils that give the cream its feel. The complete label shows all of them, in order.
PEPTIDE · 1,000 MG
Syn-Ake
Dipeptide Diaminobutyroyl Benzylamide Diacetate
A lab-made peptide used in skin care for the look of expression lines. Nothing in it comes from a snake.
The complete label listAll ingredients · in label order
- Aqua Olea Europaea (Olive) Fruit Oil Cetearyl Olivate Sorbitan Laurate Glycerin Dipeptide Diaminobutyroyl Benzylamide Diacetate (Syn-Ake) Glyceryl Stearate Cetyl Alcohol Panthenol Calendula Officinalis Flower Oil Sodium Stearoyl Glutamate Passiflora Edulis (Passion Fruit) Seed Oil Oryza Sativa (Rice) Bran Oil Euterpe Oleracea (Acai) Fruit Oil Phenethyl Alcohol Ethylhexylglycerin Glutathione Nicotinamide Mononucleotide (NMN) (GHK-Cu)
As listed on the product.
Amounts you can check
All five actives are measured per bottle on the lab report for the current lot.
Airless pump
Air and fingers stay out of the cream from the first pump to the last.
Vegan-friendly
No ingredients of animal origin are listed on the label.
One pump, morning and evening
On clean skin, after any serum and before sunscreen. Patch test before first use.
01 · One pump
02 · Smooth over linesStart where your face moves
Smooth it across your forehead, between your brows and at the outer corners of your eyes, then spread what is left. Keep it out of the eyes.
03 · Let it absorbThen sunscreen or makeup
Give it a minute to absorb. In the morning, follow with sunscreen. Makeup goes on smoothly over it.
Patch test first
Try a small amount on your jawline before first use.
Around the eyes
Use on the outer eye area only, not on the eyelids or close to the lash line.
With other actives
If you use retinol or acids, apply them at a different time or introduce the cream gradually.
Two face creams, two different jobs
The Syn-Ake cream is made for the look of expression lines. The Advanced GHK-Cu cream is a copper peptide moisturizer for the whole face. Prices update with the option you choose.
This page
Syn-Ake Peptide Face Cream
$42 a bottle
One bottle
- Lead active
- 1,000 mg Syn-Ake + GHK-Cu
- Size
- 1.69 fl oz (50 mL)
- Format
- Airless pump
- Made for
- Expression lines
Suits you if lines on your forehead, between your brows or at the outer eyes are your main concern.
Advanced GHK-Cu Face Cream
$40 a bottle
One bottle
- Lead active
- 2,400 mg GHK-Cu (4%)
- Size
- 60 g (2.12 oz)
- Format
- Jar
- Made for
- Whole-face moisture and firmness
Suits you if you want a copper peptide moisturizer for your whole face.
30-day money-back guarantee
Both are cosmetic creams for daily use. They have not been compared in a study.
What the lab measured in this lot
An independent ISO 17025 lab measured all five actives in the current lot, per bottle. Published research on Syn-Ake and GHK-Cu is a different kind of evidence: it studies the ingredients, not this cream. See the Neurogan evidence map.
Two kinds of evidence
Lab reportMeasures the actives in one lot of this cream.
Published researchStudies the ingredients, not this exact cream.
PilotVery preliminary
Syn-Ake in creams
Small supplier tests of a cream with 4% of the Syn-Ake trade ingredient, applied twice a day for 28 days, reported smoother-looking skin in most volunteers. The reports lack the methods needed for independent confirmation, and the trade ingredient level may differ from this cream.
Neurogan evidence map · Syn-AkePilotLimited evidence
GHK-Cu in leave-on creams
Small human reports on leave-on GHK-Cu creams describe fewer visible lines and less laxity. The Neurogan evidence map rates this as pilot-stage with limited evidence.
Neurogan evidence map · GHK-CuCertificate of analysis
References · Ingredient research, not studies of this finished product 2
- Neurogan Science. Syn-Ake: evidence review. Research maturity: pilot. Evidence strength: very preliminary. Read the review ↗
- Neurogan Science. GHK-Cu: evidence review (V2). Research maturity: pilot. Evidence strength: limited. Read the review ↗
What customers are saying
Reviews marked Verified Buyer are from confirmed purchases. They describe personal experiences and are not clinical evidence.
Individual results vary. These are customer experiences, not a clinical study.
Questions we hear most often
The current lot measured 1,008 mg of Syn-Ake, 310 mg of GHK-Cu, 514 mg of panthenol, 202 mg of L-glutathione and 52 mg of NMN per bottle. The amounts are per 50 mL bottle, and the full report is linked in What the lab measured.
No. It is a lab-made peptide, modeled on a peptide first found in temple viper venom. It is made in a lab, and the cream contains no snake-derived ingredients.
No. It is a cosmetic cream for the look of expression lines, and it does not work like an injection.
Give it about four weeks of twice-daily use. That is the length of the supplier’s cream tests, and results vary from person to person.
The lab measured every active we add, not only Syn-Ake: GHK-Cu, panthenol, L-glutathione and NMN as well. Revision 03 of the report also corrects an earlier analyte name from L-glutamine to L-glutathione.
Yes, on the outer eye area where crow’s feet form. Keep it off the eyelids and away from the lash line.
Yes. Let it absorb for a minute, then apply sunscreen in the morning and makeup as usual.
A light natural scent from its plant oils. There is no added fragrance listed on the label.
It depends on how much you use. The directions call for one pump morning and evening, and the airless pump lets you use the bottle down to the last dose.
Yes. If you are not happy with it for any reason, contact us within 30 days for a full refund.
Still have a question?
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Start your first four weeks
1,000 mg of Syn-Ake with copper peptide in a 50 mL airless pump.
- Five actives measured per bottle, report linked above
- Try it for 30 days, risk-free
Ships in 1–3 business days
For external use only. Avoid contact with the eyes. Patch test before first use and stop if irritation occurs. Keep out of reach of children. This cosmetic product is not intended to diagnose, treat, cure or prevent any disease.