Scientists are constantly searching nature for substances that help our body's natural ability to maintain cell health, hoping to find the key to longevity.
Urolithin A, a metabolite made by the gut’s transformation of ellagitannins found in certain foods like pomegranates, berries, and nuts, is one of those promising compounds.
Its potential health benefits are rooted in Urolithin A's ability to stimulate mitophagy — a process critical for maintaining healthy mitochondrial function and, by extension, supporting cellular vitality, promoting healthy aging [1].
We know that eating more foods rich in ellagitannins is generally good for supporting mitochondrial function.
The problem is getting a consistent amount of urolithin A to notice a significant improvement in one’s overall health. This can be due to dietary restrictions, gut health, genetics, and more, as not all bodies transform ellagitannins efficiently into Urolithin A.
This is where a high-quality Urolithin A supplement can give you an added boost to your healthy lifestyle. This article will highlight the top Urolithin A supplements on the market and why we believe these products stand out.
Key Benefits of a High-Quality Urolithin A Supplement
What makes Urolithin A such an interesting compound that has leading scientists in the longevity space excited about its potential? There are three main areas where Urolithin A is found to support overall health.
- Supports Cellular Health: Research indicates Urolithin A's role in promoting mitochondrial function, which is crucial for cellular energy and vitality [1].
- Antioxidant Potential Studies suggest Urolithin A may help manage oxidative stress, supporting the body's natural defense systems [2].
- Muscle Function: Preliminary research points to Urolithin A's potential to support muscle health and physical performance, especially in the context of aging [2, 3].
The Best Urolithin A Supplements:
- Neurogan Health Urolithin A Capsules
- Neurogan Health Urolithin A Pro
- Mitopure Timeline
- Pure Encapsulations Renual Urolithin A
- Pepeior Urolithin A 3-in-1 Supplement
- Toniiq Pomegranate Extract
Neurogan Health's Urolithin A Capsules Lead the Market
Our journey into the realm of Urolithin A supplements has been a meticulous process of innovation, research, and obsession. In collaboration with esteemed researchers at Aalborg University in Denmark, we have honed a highly pure Urolithin A supplement.
After six years of development, we proudly launched our Urolthin A capsules in 2023, made in our GMP-certified facility in San Diego, which have since become a new standard in the wellness community.
The mission was clear from the start: to deliver a high-potency, affordable Urolthin A product that seamlessly integrates into most people's daily routines.
Each serving, consisting of two capsules, delivers a significant 700 mg of pure Urolithin A — not diluted ellagitannin-rich extracts — to give you more of what you need to support new and healthy cells.
Our range of supplements, like Urolithin A, have been loved by our customers looking for high-quality supplements for supporting energy levels, exercise performance, and overall well-being at a cellular level.
Price: $51.00
Mg of Urolthin A per serving: 700 mg (2 capsules)
Mg of Urolthin A total: 42,000 mg
Total Capsules: 60
Other Ingredients: Vegetable Cellulose (Capsules)
New Urolithin A Pro+ By Neurogan
With our original Urolithin A supplement's success, we set back out to the drawing board to create a more potent formulation with improved bioavailability with our Urolithin A Pro +.
This variation contains 1000 mg of Urolithin A per serving in a vegan-friendly capsule and an ultra-micronized form of pure Urolithin A powder. The ultra-micronization process helps to increase the compound’s surface area, potentially increasing its absorption and use in the body.
We launched this maximum potency product for that extra support in muscle function and physical performance with the highest quality Urolithin A supplement in a safe concentration without breaking the bank.
Price: $80
Mg of Urolthin A per serving: 1000 mg (2 capsules)
Mg of Urolthin A total: 60,000 mg
Total Capsules: 120
Other Ingredients: Vegetable Cellulose (Capsules)
Mitopure Timeline Urolithin A
If you've been doing any research into a good Urolithin A supplement, you wouldn't have missed Mitopure Timeline Urolithin A.
Mitopure Uroltihin A Supplements has long been recognized as a pioneering brand in this space and has set a high standard for quality and scientific backing with clinical studies in the industry.
The biggest issue for most people is that Mitopure costs $125 per 1 month supply. You can opt for a subscription model for a bit of savings, but it's still a big monthly expense for most people.
While it’s acknowledged as a premium option with a price point to match, the landscape of Urolithin A supplementation has evolved since Mitopure came onto the scene, introducing a variety of options that cater to a broader audience.
It's also worth noting that for those with dietary restrictions, these aren't vegan-friendly as they contain gelatin in the softgel formula.
Price: $125
Mg of Urolthin A per serving: 500 mg (2 capsules)
Mg of Urolthin A total: 30,000 mg
Total Capsules: 60
Other Ingredients: MCT oil, Sunflower Lecithin Oil, Gelatin, Glycerol, Purified Water, Glycerol Monostearate, Red Iron Oxide Color
Pure Encapsulations Renual Uroltihin A
Pure Encapsulations is another recognized brand for high-quality Urolthin A with a trademark blend of Urolithin A, trans-resveratrol, and CoQ10 — a formula designed to support cellular health, antioxidant protection, and energy production.
This Renual formulation has multiple compounds for synergistic support, but this isn't ideal for everyone who might be after a highly pure Urolithin A supplement. Because of the additional ingredients, you're only getting 250 mg of Urolthin A per serving.
Priced at $73 for a 30-day supply of 60 capsules, this is a premium offering on the wellness market. This premium pricing may limit its accessibility to some consumers, positioning it as a luxury rather than a staple supplement.
Price: $73
Mg of Urolthin A per serving: 250 mg (2 capsules)
Mg of Urolthin A total: 7500 mg
Total Capsules: 60
Other Ingredients: Trans-Resveratrol, CoQ10, Vegetable Glycerin, Vegetarian Capsule (Cellulose, Water)
Pepeior Urolithin A 3-in-1 Supplement
Pepeior is a brand that's quite popular on Amazon for its Urolithin A 3-in-1 supplement, though we couldn't find too much about the product or brand elsewhere, like its brand ethos, production methods, research, or lab tests.
For many Amazon shoppers, this product is an appealing option because of its price point and substantial 1000 mg of Urolithin A potency. Including pomegranate extract, strawberry fruit extract, and walnut extract aims to complement Urolithin A with a spectrum of ellagitannins, potentially encouraging the body's ability to produce Urolithin A naturally.
Like the Mitopure Urolithin A supplement, this one isn't vegan-friendly as it contains gelatin in its softgel capsule formula.
While the product's formulation sounds promising, particularly for those looking for a high-dose Urolithin A supplement with additional natural extracts, there are reasons for a measured approach.
The lack of extensive information about Pepeior and its exclusive Amazon presence may raise questions about the brand's heritage, manufacturing practices, and the scientific rigor behind its product formulations, but overall many people on Amazon trust this brand and its product.
Price: $44.99
Mg of Urolthin A per serving: 1000 mg (2 capsules)
Mg of Urolthin A total: 60,000 mg
Total Capsules: 120
Other Ingredients: Proprietary Blend (Pomegranate Extract, Organic Strawberry Fruit Extract, Organic Walnut Shell Extract), Gelatin (Softgel Capsule), Vegetable Glycerin, Purified Water
Toniiq Pomegranate Extract
Ellagic acid is an antioxidant abundant in pomegranates, and it's one of the precursors to Urolithin A, which is transformed in the gut.
Rather than opting for a pure Urolithin A supplement, Toniiq presents its 42,000 mg pomegranate extract capsules with a reported 90% ellagic acid concentration for a different approach to supporting mitochondrial health and cellular renewal.
A critical consideration for those interested in this supplement is the individual variability in converting ellagic acid to Urolithin A. This metabolic process is highly dependent on one's gut microbiome and genetics, which means that the efficiency of this product can significantly vary from person to person.
We could see how this product caters to those who prefer to consume precursor compounds, allowing their body's natural processes to produce beneficial metabolites. Additionally, the high concentration of ellagic acid provides a potent dose of this antioxidant, which may offer health benefits in its own right.
Price: $44.99
Mg of Urolthin A per serving: 1000 mg (2 capsules)
Mg of Urolthin A total: 60,000 mg
Total Capsules: 120
Other Ingredients: Proprietary Blend (Pomegranate Extract, Organic Strawberry Fruit Extract, Organic Walnut Shell Extract), Gelatin (Softgel Capsule), Vegetable Glycerin, Purified Water
Where to Buy Mitopure?
The most convenient way to purchase Mitopure is on Amazon, allowing for easy ordering along with other essentials and fast shipping options.
Alternatively, Mitopure can also be bought directly from its official website. Some specialty stores in the US may carry Mitopure, but availability varies, so checking with stores individually is recommended.
Where to Buy Neurogan Health Urolithin A?
We offer our Neurogan Health Urolithin A supplements through two primary channels for your convenience.
You can find our products on Amazon, which we recommend for the most straightforward purchasing experience. Amazon's platform allows you to easily add our Urolithin A supplement to your cart alongside your other daily needs, benefiting from fast and reliable shipping.
Alternatively, you can purchase directly from our website. Buying from us directly ensures that you're getting your supplements straight from the source, along with access to the full range of our products, detailed information, and customer support dedicated to helping you with any questions you might have.
What to Look for in a Quality Urolithin A Supplement
Although Urolithin A is still a niche supplement, with growing research showing its promise for supporting cellular health, muscle function, and neuroprotective effects, we expect more supplements like this to hit the market — but not all of which will be worth your money. Here's what you should look for:
- High Purity Urolithin A: Look for supplements that specify Urolithin A contents. High purity indicates that the supplement contains a concentrated form of Urolithin A, free from unnecessary additives.
- Effective Urolithin A Concentration: Most of the research surrounding the benefits of Urolithin A for supporting cellular wellness looks at concentrations of upwards of 500 mg per serving. The concentration of Urolithin A in the supplement should be clearly stated. This information is crucial for understanding the potency of the product you're considering.
- Ethical Sourcing: Consider the source of Urolithin A and other ingredients in the supplement. Ethical sourcing practices ensure the ingredients are obtained in a way that is respectful to the environment and local communities.
- GMP Certification: Ensure the supplement is produced in a facility that is Good Manufacturing Practice (GMP) certified. This certification indicates that the manufacturing process meets the strict quality standards expected for supplements.
- Independent Lab Testing: Look for products tested by a third-party lab to verify their Uriolithin A concentration and safety profile before purchasing.
- FDA Compliance: Look for products that comply with FDA regulations, ensuring they do not make unverified health claims. Compliance with these regulations is a good indicator of a company's integrity in the wellness space.
- Positive Reviews: While you can expect individual experiences to vary with supplements, reading consumer reviews can provide insights into the effectiveness and reliability of the supplement and the company.
The Takeaway: The Best Urolthin A Supplement in 2024
There are a great handful of Urolithin A supplements out there, and we're proud to say that we've established a couple of variations of Urolithin A that meet high-quality standards, potency, and purity while still being affordable and vegan-friendly.
We hope this guide gives you better insight into discovering the top-rated Urolithin A products available with some key pointers that help you make well-informed decisions when shopping — regardless of your health aspirations.
Resources:
- D’Amico, D., Andreux, P. A., Valdés, P., Singh, A., Rinsch, C., & Auwerx, J. (2021). Impact of the natural compound urolithin A on health, disease, and aging. Trends in molecular medicine, 27(7), 687-699.
- Zhao, H., Song, G., Zhu, H., Qian, H., Pan, X., Song, X., ... & Liu, C. (2023). Pharmacological Effects of Urolithin A and Its Role in Muscle Health and Performance: Current Knowledge and Prospects. Nutrients, 15(20), 4441.
- Liu, S., & Marcinek, D. (2021). Urolithin A enhances muscle performance in elderly and positively impacts biomarkers linked to cellular health. Innovation in Aging, 5(Suppl 1), 671.
