Scientists are constantly searching nature for substances that help our body's natural ability to maintain cell health, hoping to find the key to longevity.
Urolithin A, a metabolite made by the gut’s transformation of ellagitannins found in certain foods like pomegranates, berries, and nuts, is one of those promising compounds.
Its potential health benefits are rooted in Urolithin A's ability to stimulate mitophagy — a process critical for maintaining healthy mitochondrial function and, by extension, supporting cellular vitality, promoting healthy aging [1].
We know that eating more foods rich in ellagitannins is generally good for supporting mitochondrial function.
The problem is getting a consistent amount of urolithin A to notice a significant improvement in one’s overall health. This can be due to dietary restrictions, gut health, genetics, and more, as not all bodies transform ellagitannins efficiently into Urolithin A.
This is where a high-quality Urolithin A supplement can give you an added boost to your healthy lifestyle. This article will highlight the top Urolithin A supplements on the market and why we believe these products stand out.
Key Benefits of a High-Quality Urolithin A Supplement
What makes Urolithin A such an interesting compound that has leading scientists in the longevity space excited about its potential? There are three main areas where Urolithin A is found to support overall health.
- Supports Cellular Health: Research indicates Urolithin A's role in promoting mitochondrial function, which is crucial for cellular energy and vitality [1].
- Antioxidant Potential Studies suggest Urolithin A may help manage oxidative stress, supporting the body's natural defense systems [2].
- Muscle Function: Preliminary research points to Urolithin A's potential to support muscle health and physical performance, especially in the context of aging [2, 3].
The Best Urolithin A Supplements:
- Neurogan Health Urolithin A Capsules
- Neurogan Health Urolithin A Pro
- Mitopure Timeline
- Pure Encapsulations Renual Urolithin A
- Toniiq Pomegranate Extract
Neurogan Health's Urolithin A Capsules Lead the Market
Our journey into Urolithin A supplements has been a process of innovation, research, and obsession. In collaboration with researchers at Aalborg University in Denmark, we have found a solution to a highly pure Urolithin A supplement.
After six years of development, we proudly launched our Urolthin A capsules in 2023, made in our GMP-certified facility in San Diego.
The mission was clear from the start: to deliver a high-potency, affordable Urolthin A product that seamlessly integrates into most people's daily routines.
Each serving, consisting of two capsules, delivers a significant 700 mg of pure Urolithin A — not diluted ellagitannin-rich extracts — to give you more of what you need to support new and healthy cells.
Our range of supplements, like Urolithin A, have been loved by our customers looking for high-quality supplements for supporting energy levels, exercise performance, and overall well-being at a cellular level.
Price: $51.00
Mg of Urolthin A per serving: 700 mg (2 capsules)
Mg of Urolthin A total: 42,000 mg
Total Capsules: 60
Other Ingredients: Vegetable Cellulose (Capsules)
New Urolithin A Pro+ By Neurogan
With our original Urolithin A supplement's success, we set back out to the drawing board to create a more potent formulation with improved bioavailability with our Urolithin A Pro +.
This variation contains 1000 mg of Urolithin A per serving in a vegan-friendly capsule and an ultra-micronized form of our pure Urolithin A powder. The ultra-micronization process helps to increase the compound’s surface area, potentially increasing its absorption and use in the body.
We launched this maximum potency product for that extra support for physical performance with the highest quality Urolithin A supplement in a safe concentration without breaking the bank.
Neurogan Health Shipping: We ship worldwide, including Australia, Canada & the UL. Shipping costs are up to $50, with a maximum delivery time of 10 days.
Price: $80 (varies)
Mg of Urolthin A per serving: 1000 mg (2 capsules)
Mg of Urolthin A total: 60,000 mg
Total Capsules: 120
Other Ingredients: Vegetable Cellulose (Capsules)
Neurogan Health Urolithin A Reviews:
1. “After a week, I feel instant energy and vitality after taking it. I can tell it’s working on the mitochondria in my cells. My skin looks better as well.”
2. “I’ve experienced a boost in energy, almost eliminating afternoon slumps and enhancing my workouts. My muscle strength and endurance seemed to improve, making exercise routines easier and more effective.”
3. “I bought this to help with post-workout repair. It seems to work because I feel less tired after taking it, and my muscles don’t feel as sore.”
Mitopure Timeline Urolithin A
If you've been doing any research into a good Urolithin A supplement, you wouldn't have missed Mitopure Timeline Urolithin A.
Mitopure Uroltihin A Supplements is the pioneering brand in this space and has set a high standard for quality and scientific backing with clinical studies in the industry.
The biggest issue for most people is that Mitopure costs $125 per 1 month supply. You can opt for a subscription model for a bit of savings, but it's still a big monthly expense for most people.
While it’s seen as a premium option with a matching price, Urolithin A supplementation has evolved. Timeline ships to the UK, Canada, and the United States within 1-3 business days but does not ship to Australia.
It's also worth noting that for those with dietary restrictions, their old formula for urolithin a were not vegan, as they contained Gelaton. However, Mitopure have now switched over to vegan softgels & have done an excellent job in adding additional ingredients to their softgels, which many other market competitors haven't.
Price: $125
Mg of Urolthin A per serving: 500 mg (2 capsules)
Mg of Urolthin A total: 30,000 mg
Total Capsules: 60
Timeline (mitopure) Ingredients: MCT oil, Sunflower Lecithin Oil, Glycerol, Purified Water, Glycerol Monostearate, Red Iron Oxide Color.
Mitopure Urolithin A Reviews:
1. “For increased energy before and after my workout. I’ve been using this product for over a year, and it has definitely made a difference in my stamina and strength.”
2. “I was taking longer to process responses and having trouble thinking of words mid-conversation. I started this product, and the fogginess cleared the same day.”
3. “It really helps with energy, muscle strength, and endurance. I’m a runner, and it’s helping me tremendously.”
Pure Encapsulations Renual Uroltihin A
Pure Encapsulations is another recognized brand for high-quality Urolthin A with a trademark blend of Urolithin A, trans-resveratrol, and CoQ10 — a formula designed to support cellular health, antioxidant protection, and energy production.
This Renual formulation has multiple compounds for synergistic support, but this isn't ideal for everyone who might be after a highly pure Urolithin A supplement. Because of the additional ingredients, you're only getting 250 mg of Urolthin A per serving.
Priced at $73 for a 30-day supply of 60 capsules, this is a premium offering on the wellness market. This premium pricing may limit its accessibility to some consumers, positioning it as a luxury rather than a staple supplement.
Price: $73
Mg of Urolthin A per serving: 250 mg (2 capsules)
Mg of Urolthin A total: 7500 mg
Total Capsules: 60
Other Ingredients: Trans-Resveratrol, CoQ10, Vegetable Glycerin, Vegetarian Capsule (Cellulose, Water)
Toniiq Pomegranate Extract
Ellagic acid is an antioxidant abundant in pomegranates, and it's one of the precursors to Urolithin A, which is transformed in the gut.
Rather than opting for a pure Urolithin A supplement, Toniiq presents its 42,000 mg pomegranate extract capsules with a reported 90% ellagic acid concentration for a different approach to supporting mitochondrial health and cellular renewal.
A critical consideration for those interested in this supplement is the individual variability in converting ellagic acid to Urolithin A. This metabolic process is highly dependent on one's gut microbiome and genetics, which means that the efficiency of this product can significantly vary from person to person.
We could see how this product caters to those who prefer to consume precursor compounds, allowing their body's natural processes to produce beneficial metabolites. Additionally, the high concentration of ellagic acid provides a potent dose of this antioxidant, which may offer health benefits in its own right.
Price: $44.99
Mg of Urolthin A per serving: 1000 mg (2 capsules)
Mg of Urolthin A total: 60,000 mg
Total Capsules: 120
Other Ingredients: Proprietary Blend (Pomegranate Extract, Organic Strawberry Fruit Extract, Organic Walnut Shell Extract), Gelatin (Softgel Capsule), Vegetable Glycerin, Purified Water
Where to Find Neurogan Health's Urolithin A?
We offer our Neurogan Health Urolithin A supplements through two primary channels for your convenience.
You can find all our Urolithin A Supplements products on Amazon, which we recommend for the most straightforward purchasing experience. Amazon's platform allows you to easily add our Urolithin A supplement to your cart alongside your other daily needs, benefiting from fast and reliable shipping.
Alternatively, you can purchase directly from our website. Buying from us directly ensures a 25% subscription option, along with access to the full range of products, detailed information, and 24/7 customer support.
Shipping times may be longer compared to local options, but you’ll receive products straight from the source.
What Happened To Pepeior Urolithin A Supplements?
Pepeior was a brand known on Amazon for its Urolithin A 3-in-1 supplement, offering a substantial 1000 mg of Urolithin A per serving. The formula included pomegranate extract, strawberry fruit extract, and walnut extract to provide a range of ellagitannins, potentially supporting the body’s natural production of Urolithin A.
However, their product listing has been removed from Amazon, and they do not have an official website or any other verified online presence. This lack of available information about their brand ethos, production methods, research, and lab testing, combined with their limited presence, means we can no longer include them in our selection of six products.
What to Look for in a Quality Urolithin A Supplement
Urolithin A is still a niche supplement, with growing research showing its promise for supporting cellular health, muscle function, and neuroprotective effects, we still expect more supplements like this to hit the market — but not all of which will be worth your money. Here's what you should look for:
- High Purity Urolithin A: Look for supplements that specify Urolithin A contents. High purity indicates that the supplement contains a concentrated form of Urolithin A, free from unnecessary additives.
- Effective Urolithin A Concentration: Most of the research surrounding the benefits of Urolithin A for supporting cellular wellness looks at concentrations of upwards of 500 mg per serving. The concentration of Urolithin A in the supplement should be clearly stated. This information is crucial for understanding the potency of the product you're considering.
- Ethical Sourcing: Consider the source of Urolithin A and other ingredients in the supplement. Ethical sourcing practices ensure the ingredients are obtained in a way that is respectful to the environment and local communities.
- GMP Certification: Ensure the supplement is produced in a facility that is Good Manufacturing Practice (GMP) certified. This certification indicates that the manufacturing process meets the strict quality standards expected for supplements.
- Independent Lab Testing: Look for products tested by a third-party lab to verify their Uriolithin A concentration and safety profile before purchasing.
- FDA Compliance: Look for products that comply with FDA regulations, ensuring they do not make unverified health claims. Compliance with these regulations is a good indicator of a company's integrity in the wellness space.
- Positive Reviews: While you can expect individual experiences to vary with supplements, reading consumer reviews can provide insights into the effectiveness and reliability of the supplement and the company.
Our Unbiased Reviews & Selections for Urolithin A
There are a great handful of Urolithin A supplements out there, and we're proud to say that we've established a couple of variations of Urolithin A that meet high-quality standards, potency, and purity while still being affordable and vegan-friendly.
We hope this guide gives you better insight into a potential start with Urolithin A products. Hopefully key pointers will help you make well-informed decisions when shopping — regardless of your health aspirations.
Resources:
- D’Amico, D., Andreux, P. A., Valdés, P., Singh, A., Rinsch, C., & Auwerx, J. (2021). Impact of the natural compound urolithin A on health, disease, and aging. Trends in molecular medicine, 27(7), 687-699.
- Zhao, H., Song, G., Zhu, H., Qian, H., Pan, X., Song, X., ... & Liu, C. (2023). Pharmacological Effects of Urolithin A and Its Role in Muscle Health and Performance: Current Knowledge and Prospects. Nutrients, 15(20), 4441.
- Liu, S., & Marcinek, D. (2021). Urolithin A enhances muscle performance in elderly and positively impacts biomarkers linked to cellular health. Innovation in Aging, 5(Suppl 1), 671.
