01 · Clean skinCleanse and pat dry
Cleanse the face, neck and upper chest, then pat the skin dry before the serum.
GHK-Cu Copper Peptide Face & Neck Serum holds 1,200 mg of GHK-Cu (Copper Tripeptide-1) at 4% in a 1 oz (30 mL) bottle, with niacinamide, aloe vera, glycerin and light plant oils.
It is made for the neck and upper chest as well as the face, where dryness and fine lines often show first.
A lockable pump measures out each application and closes for travel.
A high-strength GHK-Cu serum for daily skin care, from the Neurogan Health copper peptide range. With consistent use it is designed to support smoother-looking texture, visible firmness, hydration and a more even-looking complexion.
1,200 mg is the amount per bottle, which in 30 mL is 40 mg per mL, the 4% printed on the label.
Copper Tripeptide-1 is the ingredient-list name for GHK-Cu: glycyl-L-histidyl-L-lysine bound to copper.
Batch result. The current lot (DK25-CPD01-4) measured 1,255 mg of GHK-Cu per bottle against a 1,200 mg specification. The product strength stays 1,200 mg.
Advanced is its own formula. Our GHK-Cu Neck & Face Serum in the amber dropper bottle is a different product.
Adults who want to support smoother-looking texture and visible firmness, who prefer a light serum to a rich cream, and who want one product for the face, neck and décolletage.
This is a cosmetic product, not an overnight wrinkle treatment, and not a treatment for any skin condition.
GHK-Cu works best as part of a steady routine with gentle cleansing, moisturizer and daily sunscreen. Changes are gradual, and results vary.
It contains lemon peel oil and lemon essential oil, so it is not fragrance-free.
Published GHK-Cu research is small and mostly on creams. It is not clinical evidence for this finished serum.
Sisse Marie, one of the family founders of Neurogan Health, walks through what is in the serum, what GHK-Cu is and how to press and pat it into the skin.
In this video
Individual results vary. This is a cosmetic product.
The copper peptide is the active. Everything else carries it, holds water at the skin surface or keeps the serum light.
COPPER PEPTIDE ACTIVE
Copper Tripeptide-1
The active, at 1,200 mg in each bottle. GHK-Cu is used in cosmetics for smoother, firmer-looking skin, and it turns the serum blue.
In label order, with standard ingredient names.
The blue comes from GHK-Cu itself, not from an added dye.
Lemon peel oil and lemon essential oil give the serum its scent, so it is not fragrance-free.
Phenoxyethanol with ethylhexylglycerin protects the water-based serum once the pump is in use.
Skin renews itself gradually, so judge a peptide serum over weeks, not days. Here is what each stage usually brings, with words from customers who reviewed it.
Day 1
Before the first application, photograph your face, neck and upper chest in daylight. Compare monthly rather than daily, in the same light.
“It absorbed so quickly and the smell is amazing.” Carla W.
Weeks 1 to 3
As your skin gets used to the serum, the first changes people describe are in how it feels: more hydrated, softer and more comfortable.
“Noticed a nice healthy glow after one week of using nightly.” Nathalie L.
Weeks 4 to 8
With daily use, many people begin to notice smoother-looking texture. This is a good point to compare photos taken in the same light.
“Around week 8 I started noticing a real change in my skin.” Hilda S.
Weeks 9 to 12
Longer use may support softer-looking fine lines and visible firmness. Results depend on age, sun exposure, routine and skin condition.
“After consistent use, I noticed a visible improvement in my skin’s overall texture.” Megan A.
Quotes are from verified customer reviews of this serum and describe individual experiences, not a clinical study. Results vary. This is a cosmetic product.
Morning or evening both work. Start once a day and choose the routine you will keep.
01 · Clean skinCleanse the face, neck and upper chest, then pat the skin dry before the serum.
02 · A thin layerPump a small amount onto your fingertips, then press and pat it over the face, neck and décolletage. It takes 1 to 2 minutes to absorb; wait until it has before the next step.
03 · FinishFollow with your moisturizer or our GHK-Cu face cream, and finish with broad-spectrum sunscreen in the morning.
Pilling usually means too much serum or too little drying time. Use a thinner layer, press rather than rub, and give it the full 1 to 2 minutes to absorb before moisturizer and sunscreen. Some customers keep it for the evening.
It contains lemon peel oil and lemon essential oil. Patch test for 24 hours first, start every other day if your skin is reactive, and keep it away from your eyes.
Strong actives are easier in a separate routine, for example the serum in the morning and retinol at night. With prescription skin care, ask your clinician first.
Pairs well with a gentle cleanser, a moisturizer or hyaluronic acid on top, and a broad-spectrum SPF 30+ every morning.
A certificate of analysis documents what was tested in one batch of this serum. Published research on GHK-Cu is a different kind of evidence: it studies the ingredient, mostly in creams, not this finished serum. See the Neurogan evidence map.
Two kinds of evidence
Small human reports on leave-on GHK-Cu creams describe fewer visible lines and wrinkles and less laxity. The Neurogan evidence map rates this research as pilot-stage with limited evidence. These studies tested creams, not this serum.
Neurogan evidence map · GHK-CuOur two face serums and the 4% cream, with today's price per day. No study has compared them, so pick the texture and bottle you will reach for every day.

$51 a bottle
$1.70 a day · lasts about 30 days
Suits you if you want the Advanced formula in a pump that locks for travel.
A subscription, delivered every 2 months. Pause or cancel any time.

$40 a bottle
$0.67 a day · lasts about 60 days
Suits you if you prefer a dropper and a lower price.

$50 a bottle
$0.83 a day · lasts about 60 days
Suits you if you want one step that also moisturizes, or a cream over the serum at night.
30-day money-back guarantee
Days per bottle or jar assume daily use and depend on how much you apply.
Reviews marked Verified Buyer are from confirmed purchases. They describe personal experiences with this serum and are not clinical evidence.
Individual results vary. These are customer experiences, not a clinical study.
Hydration and softness may show first. Changes in texture, fine lines or visible firmness can take 8 to 12 weeks to judge. Results vary.
It is a separate formula in a frosted bottle with a lockable pump, and its label states 1,200 mg of GHK-Cu at 4%. The GHK-Cu Neck & Face Serum comes in amber glass with a dropper and costs less. Compare them.
Some people apply it morning and evening, but twice a day is not automatically better. Start once a day and add a second application only if your skin stays comfortable.
Yes. Let it absorb, then apply moisturizer and sunscreen before makeup.
No. No topical cosmetic permanently removes wrinkles. It may help fine lines look softer by supporting hydration and overall skin quality.
The blue comes from the copper in GHK-Cu, and the shade can vary a little between batches. If yours looks very different from your last bottle, contact us with the lot number.
No. It contains lemon peel oil and lemon essential oil, and many reviewers mention the scent.
There is no known withdrawal effect. Any cosmetic changes from steady use may fade gradually after you stop.
We offer a 30-day money-back guarantee. If you are not happy for any reason, contact us and we will give you a full refund.
1,200 mg of GHK-Cu at 4%, with niacinamide and aloe, in a 1 oz lockable pump bottle.
Adds a subscription, delivered every 2 months (about one bottle per delivery).
For external use only. Avoid direct contact with the eyes. Patch test before use. Discontinue use if persistent irritation occurs. Keep out of reach of children. This cosmetic product is not intended to diagnose, treat, cure or prevent any disease.