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Most conversations about spermidine focus on food sources and supplements. Food like wheat germ, aged cheese, or spermidine supplements are the mos...

Caloric restriction (eating significantly less without becoming malnourished)  is one of the most consistently studied ways to extend lifespan in l...

You need both vitamins C and D — it isn't a competition. Most people are low in one or the other, so it's a good idea to supplement with these comp...

Spermidine supports autophagy, which is the body’s built-in cleanup mode. Resveratrol activates pathways linked to longevity genes and mimics some ...

For most healthy adults, spermidine appears to be safe at the doses used in clinical research and food-based supplementation.  The European Food Sa...

Fasting has a reputation problem. Depending on who you ask, it’s either the single most powerful longevity tool available or a dressed-up eating di...

The Mediterranean diet doesn’t need another endorsement. Decades of research have already tied this eating pattern to lower rates of cardiovascular...

Your immune system gets weaker with age. The complex machinery that keeps immune cells functional slowly breaks down with misfired signals, old thr...

The short answer: maybe, but the evidence is still early.  A handful of studies (including one clinical trial) suggest that spermidine may support ...

Aging doesn’t happen all at once.  It creeps in through a handful of biological processes that reinforce each other, and three of the most conseque...

The short answer: spermidine looks genuinely promising for brain health, but we’re not at “proven” yet. The longer answer is more interesting and w...

Of all the organs that age alongside us, the heart may be the one we notice last, and the one where age-related decline matters most.  Cardiovascul...