Peptides are short chains of amino acids, the building blocks of proteins. Unlike proteins, peptides are smaller and more easily absorbed by the body, which is why they’ve become so popular in the supplement industry. These are naturally occurring compounds in the body that play various roles, from hormonal regulation to tissue repair [1].
The intrigue surrounding peptides in the context of hair health stems primarily from research and anecdotal evidence suggesting their potential role in supporting hair wellness.
In this blog post, we'll highlight some of the top wellness supplements associated with potential hair health support. These include a variety of peptide supplements that have been the subject of research and user experiences in the context of hair care.
Please understand that hair loss is complex and can be influenced by many factors, including genetics and lifestyle. Therefore, while peptides may offer some potential health benefits, they're not a cure or prevent treatment for hair loss or any other health condition.
How Do Peptides Help Hair Growth?
Peptides like copper peptides, biotinoyl tripeptide-1, and acetyl tetrapeptide-3 may help hair and scalp health in several ways.
Think of your hair as a flourishing garden, where each hair strand is a plant. Just like plants need nutrients and a healthy environment (scalp health) to grow, your hair needs the right conditions and building blocks to grow healthily.
Hair is primarily made up of a protein called keratin. Peptides are short chains of amino acids — the same building blocks that create proteins. When we talk about peptides in the context of hair growth, we're looking at how these small amino acid chains can support your hair's keratin structure.
On top of this, some peptides have been observed to have anti-inflammatory properties, which may support general scalp health, which is the foundation for promoting hair growth [2].
The Role of Peptides in the Hair Growth Cycle
Hair growth occurs in a cycle that includes:
- Growth (anagen)
- Regression (catagen)
- Resting (telogen)
- Shedding (exogen) phases
Peptides are thought to play a role in this cycle, particularly in the anagen phase, where they may help promote a healthy environment for hair growth [3]. They might do this by providing the scalp with essential nutrients or supporting the hair follicles, like the 'seeds' from which your hair grows.
Some peptides are believed to have antioxidant properties, which means they can combat oxidative stress — a factor that can contribute to hair aging and hair loss. By potentially supporting the body in combating oxidative stress and inflammation, peptides might create a more conducive environment for hair growth [2].
While the potential benefits of peptides for hair growth are backed by some scientific studies and anecdotal evidence, it's important to remember that research in this area is still ongoing. Not all studies yield consistent results, and what works for one person might not work for another.
The 5 Best Peptide Supplements for Hair Growth
We've rounded up a short list of the top peptide products that may support your journey for healthy hair, but please keep in mind that while these products are loved by many, they're not a one-size-fits-all solution to hair thinning.
How they work can vary based on individual factors like genetics, overall health, lifestyle, and reason for hair loss.
It's also a good idea to take a moment to read through the usage instructions and added ingredients of products. And, for that extra piece of mind, chatting with your healthcare provider to make sure these options are safe for you is always a good idea.
1. Neurogan Health GHK-Cu (Copper Peptide) Tablets
GHK-Cu, known as copper peptides, in tablet form is typically used for its potential benefits in skin health, healthy aging, and hair health.
Copper peptides are believed to stimulate collagen and elastin production, which is essential for maintaining skin elasticity and firmness. In the context of hair, GHK-Cu is thought to possibly strengthen and thicken hair by stimulating hair follicle growth. This is due to its potential role in increasing blood circulation to the scalp and reducing inflammation, creating a healthier environment for hair growth [4].
Those who choose Neurogan health Copper Peptide tablets can expect a product that aligns with our San Diego GMP-certified facility's high manufacturing and quality control standards.
GMP certification (Good Manufacturing Practices (GMP) is crucial as it ensures products are consistently produced and controlled according to strict industry quality standards, especially when it comes to peptides.
The dosing of 120 mcg of GHK-Cu per tablet takes the guesswork out of supplementation. This consistency is a valuable feature for those who are meticulous about their supplement regimens, ensuring they get the exact amount of GHK-Cu they intend to take each day.
2. Sports Research Collagen Peptides Powder
Sports Research Collagen Peptides Powder is a popular dietary supplement known for its high-quality collagen content. This product primarily contains hydrolyzed type I and III collagen sourced from bovine. These types of collagen are known for their role in maintaining the health of skin, nails, and hair.
Each serving typically provides a significant amount of collagen, which is beneficial as it’s a primary protein in the body and a key component of hair. The powder form makes it versatile for use; it can be easily mixed into liquids like water, coffee, or smoothies.
Collagen is believed to provide amino acids that can help to build hair. Its potential benefits for hair health may include supporting hair strength and elasticity. The presence of amino acids like proline, which is a component of keratin (the protein that hair is made of), is one of the reasons it might be beneficial for hair health.
While Sports Research Collagen Peptides Powder is appreciated for its quality and ease of use, it's important to remember that results can vary from person to person.
3. The Ordinary Multi-Peptide Serum for Hair Density
The Ordinary Multi-Peptide Serum for Hair Density is a specialized scalp treatment designed to support hair health and improve hair density. This serum is part of The Ordinary's range of minimalistic, scientifically formulated skincare and hair care products.
The serum includes a concentration of multiple peptide complexes, such as Biotinoyl Tripeptide-1, Acetyl Tetrapeptide-3, and others. These peptides are known for their potential role in strengthening hair and improving scalp health. Their serum contains proprietary ingredients such as Redensyl® and Procapil™ aimed at targeting hair follicles, as well as caffeine and hyaluronic acid for their blood circulation and scalp moisturizing properties.
The serum is designed for easy application with a dropper and is meant to be applied directly to a clean, dry scalp, preferably at bedtime. The product is lightweight and is absorbed quickly without leaving a greasy residue.
Its formula is a blend of scientifically backed components, making it a comprehensive solution for those looking to support hair density and scalp health.
4. DS Laboratories Spectral.DNC-N®
DS Laboratories Spectral.DNC-N® is a topical hair loss treatment designed to support hair health and address thinning hair. It features a blend of ingredients, including copper peptides and Nanoxidil 5%, a key component in this formula.
Nanoxidil is a compound similar to minoxidil and is widely used in hair growth products. It's a topical treatment designed to help stimulate hair growth and prevent hair loss.
Combining Nanoxidil with copper peptides is notable because it combines two approaches to supporting hair health. Nanoxidil primarily stimulates hair growth, while copper peptides are believed to have several beneficial effects on hair and scalp health.
5. Nutrafol® Hair Growth Supplement
Nutrafol® aims to target multiple root causes of hair thinning, such as hormonal imbalance, stress, and inadequate nutrition. The blend of natural ingredients is designed to work synergistically to support healthy hair growth.
It has a mix of collagen peptides, vitamins, and adaptogenic herbs for a holistic approach to tackling new hair growth. While many users have reported positive results, outcomes can differ from person to person, and patience and consistency are key when using this supplement.
Injectable Peptides for Hair Growth
Injectable peptide treatments specifically for hair growth are not mainstream but can be found in specialized skin and hair clinics offered by professionals. An example of this would be microneedling treatments combined with peptide injections.
Microneedling involves creating tiny punctures in the scalp, followed by applying peptide solutions to the scalp. The idea is that the micro-injuries stimulate the body's natural healing processes, and when combined with peptides, this can potentially encourage hair growth.
This isn't something you can DIY at home, so if you're interested in microneedling peptide therapy, you should consult with a trusted clinic. One of the benefits of trying supplements is that you don’t have to go through minimally invasive procedures, you can start your hair growth journey from the inside out before committing time, money, and pain.
The 3 Best Peptides for Hair Growth (According To Research)
1. Copper Peptides (GHK-Cu)
If you couldn't already tell, we're all about copper peptides when it comes to skin and hair health. Some studies have indicated that copper peptides can help support new hair follicles and improve scalp health by increasing blood flow and supporting healthy inflammation [5].
2. Biotinoyl Tripeptide-1
Biotinoyl Tripeptide-1 is a combination of biotin (a B vitamin) and a tripeptide. Biotin is known for its role in strengthening hair and nails. This compound is often included in shampoos, conditioners, and hair treatments. It is believed to strengthen the hair, reduce hair loss, and improve hair health [6].
3. Acetyl Tetrapeptide-3
Acetyl Tetrapeptide-3 is a synthetic peptide used in hair care products. This peptide is sometimes combined with red clover extract in hair care formulations. It's thought to improve the extracellular matrix proteins in the scalp, creating a better environment for healthy hair growth [7].
Peptide for Hair: Side Effects
Taking peptide supplements may result in:
- Scalp irritation
- Allergic reactions
- Hair greasiness
- Product buildup
That being said, most peptides are safe to take, even in higher doses.
Before trying any hair care products with active ingredients, conducting a patch test on your skin is a good idea to ensure you're not sensitive to any ingredients. If you're taking any other topical medication, speak with your healthcare provider before starting any peptide treatments.
Do Peptides Cause Hair Loss?
No, peptides themselves do not typically cause hair loss. However, excessive use of products containing peptides can lead to scalp buildup or irritation, which, in some cases, might exacerbate hair loss. It's important to use these products as directed and monitor your scalp's response to them.
The Takeaway: Peptides for Hair Growth
It's important to recognize that supplements, including peptides, are not cure-alls for hair loss.
Hair loss is complex and varies greatly among individuals, depending on factors like genetics and lifestyle. While supplements might support hair health as part of a holistic approach, they're not standalone solutions for hair loss.
For a well-rounded hair loss strategy, consult with healthcare professionals who can offer tailored advice, ensuring any supplements used to align with your specific health needs and overall hair loss management plan.
Remember, supplements and topical products can complement your hair care routine but should be part of a broader, professional-guided approach.
Resources:
- Forbes, J., & Krishnamurthy, K. (2020). Biochemistry, Peptide.
- Lee, W. J., Sim, H. B., Jang, Y. H., Lee, S. J., & Yim, S. H. (2016). Efficacy of a complex of 5-aminolevulinic acid and glycyl-histidyl-lysine peptide on hair growth. Annals of Dermatology, 28(4), 438-443.
- Kubanov, A. A., Gallyamova, Y. A., & Korableva, O. A. (2018). A Randomized study of biomimetic peptides efficacy and impact on the growth factors expression in the hair follicles of patients with Telogen Effluvium. Journal of Applied Pharmaceutical Science, 8(4), 015-022.
- Pyo, H. K., Yoo, H. G., Won, C. H., Lee, S. H., Kang, Y. J., Eun, H. C., ... & Kim, K. H. (2007). The effect of tripeptide-copper complex on human hair growth in vitro. Archives of pharmacal research, 30, 834-839.
- Uno, H., & Kurata, S. (1993). Chemical agents and peptides affect hair growth. Journal of investigative dermatology, 101(1), S143-S147.
- Sadgrove, N., Batra, S., Barreto, D., & Rapaport, J. (2023). An Updated Etiology of Hair Loss and the New Cosmeceutical Paradigm in Therapy: Clearing ‘the Big Eight Strikes’. Cosmetics, 10(4), 106.
- Loing, E., Lachance, R., Ollier, V., & Hocquaux, M. (2013). A new strategy to modulate alopecia using a combination of two specific and unique ingredients. J Cosmet Sci, 64(1), 45-58.
