Bryan Johnson Supplements List & Stack (2026 Updated)
Bryan Johnson
Entrepreneur & Longevity Enthusiast
Last Updated: | Reading Time: 11 min
Bryan Johnson's supplement stack has changed substantially over the past few years.
His original Project Blueprint became famous for the sheer number of pills and individual compounds in his daily routine. In 2026, Johnson presents the broader system as his Don't Die protocol, while many of the supplements he previously took individually have been consolidated into Blueprint products such as Longevity Mix, Essential Capsules and Advanced Antioxidants.1
That distinction matters because many Bryan Johnson supplement lists online still mix older versions of his routine with what he currently publishes.
Based on Johnson's current protocol, his morning supplement routine includes Longevity Mix, additional creatine, several prebiotic fibers, Essential Capsules, Advanced Antioxidants, Ashwagandha + Rhodiola and EPA/DHA. His breakfast routine also includes collagen peptides and other nutritional products.1
This article separates his current supplement stack from older protocols, prescription medications and experimental interventions that are sometimes incorrectly grouped together.
Johnson's protocol is highly individualized and changes over time. His personal routine should not be treated as a general supplement recommendation or medical protocol.
Bryan Johnson's Current Supplement List
Johnson publishes his daily schedule as part of his current Don't Die protocol. His early-morning supplement routine includes:1
| Supplement | Current Published Use | Format |
|---|---|---|
| Blueprint Longevity Mix | 1 scoop | Powder |
| Creatine | 5 g additional creatine; Johnson states Longevity Mix provides another 2.5 g | Powder |
| Galactooligosaccharides | 1/2 teaspoon | Prebiotic powder |
| Inulin | 1 teaspoon | Prebiotic fiber |
| Arabinogalactan | 1 teaspoon | Prebiotic powder |
| Blueprint Essential Capsules | 2 capsules | Capsules |
| Blueprint Advanced Antioxidants | 1 capsule | Capsule |
| Ashwagandha + Rhodiola | 1 capsule | Capsule |
| EPA/DHA | 800 mg | Omega-3 supplement |
| Collagen peptides | 11 g with breakfast | Powder |
Johnson also uses products such as Longevity Protein, Metabolic Protein, extra virgin olive oil, berries and Blueberry Nut Mix as part of his broader nutrition routine.1
The important distinction is that his current routine is no longer best described simply by counting bottles or pills. Several Blueprint products combine many ingredients into a single serving.
What's in Bryan Johnson's Essential Capsules?
Essential Capsules are one of the main multi-ingredient products in Johnson's current morning routine.
The current formula contains 23 listed longevity actives, including vitamins and minerals alongside compounds such as:2
- Nicotinamide riboside chloride (NR)
- Glucoraphanin
- Fisetin
- Luteolin
- Ubiquinol (CoQ10)
- Spermidine
- Lactobacillus acidophilus
- Boron
- Lithium orotate
- Vitamin D
- Vitamin E
- B vitamins
- Zinc
- Selenium
Blueprint currently directs users to take two capsules in the morning with food.2
This is one reason older Bryan Johnson supplement lists can be misleading. Ingredients such as NR, fisetin, luteolin, spermidine and CoQ10 may now appear inside a combined formula rather than as separate supplements.
What's in Bryan Johnson's Longevity Mix?
Johnson starts his day with one scoop of Blueprint Longevity Mix.1
The formula includes compounds such as:
- Creatine monohydrate
- Calcium alpha-ketoglutarate (CaAKG)
- Taurine
- Glycine
- Glutathione
- Lysine
- Magnesium
- L-theanine
- Vitamin C
- Glucosamine sulfate
- Sodium hyaluronate
Blueprint describes Longevity Mix as a multi-ingredient morning drink rather than a single-compound supplement.3
Johnson's current protocol also lists an additional 5 g of creatine alongside the 2.5 g supplied by Longevity Mix, for a stated total of 7.5 g of creatine.1
What's in Bryan Johnson's Advanced Antioxidants?
Johnson's current morning routine also includes one Blueprint Advanced Antioxidants capsule.1
The current formula contains seven fat-soluble nutrients:4
- Vitamin K1
- Vitamin K2 MK-4
- Vitamin K2 MK-7
- Lycopene
- Astaxanthin
- Lutein
- Zeaxanthin
Blueprint recommends taking one capsule daily with food and currently positions the formula alongside Longevity Mix and Essential Capsules as part of Johnson's morning supplement routine.4
Does Bryan Johnson Take NMN or NAD+?
Johnson's current 2026 supplement routine does not list a separate oral NMN supplement.
Instead, his Essential Capsules contain nicotinamide riboside chloride (NR), another NAD+ precursor.2
This is worth clarifying because older versions of his protocol, and many third-party supplement lists, refer to NMN, NR or alternating between the two.
Those older lists should not automatically be presented as his current routine.
As of his current published protocol, the more precise answer is:
Bryan Johnson currently consumes NR through Essential Capsules, while separate oral NMN is not listed in his published daily supplement stack.12
Does Bryan Johnson Take Creatine?
Yes.
Creatine remains one of the more prominent individual ingredients in Johnson's current routine.
His published protocol lists 5 g of additional creatine along with approximately 2.5 g supplied by Longevity Mix, which Johnson describes as a total of 7.5 g.1
That is Johnson's personal protocol rather than evidence that everyone needs the same amount.
Does Bryan Johnson Take Ashwagandha?
Yes.
Johnson currently lists one Blueprint Ashwagandha + Rhodiola capsule in his morning routine.1
The current product combines ashwagandha with Rhodiola rosea and is intended to be taken in the morning with food.5
That differs from older supplement lists that may show ashwagandha as a separate standalone supplement or at a different dose.
Does Bryan Johnson Take Omega-3?
Yes.
Johnson's current protocol lists 800 mg of EPA/DHA in his morning routine.1
Does Bryan Johnson Take Collagen?
Yes.
Johnson's current protocol lists 11 g of collagen peptides with his morning breakfast.1
Collagen therefore remains part of his current routine even though many of his other individual supplements have been consolidated into multi-ingredient Blueprint products.
Does Bryan Johnson Take Spermidine?
Yes, but it is not currently listed as a separate bottle in his main morning stack.
Spermidine is one of the ingredients included in Blueprint Essential Capsules.2
This is another example of why comparing Johnson's 2026 routine with older supplement lists can cause confusion. A compound may still be present even when the standalone supplement has disappeared.
Does Bryan Johnson Take Fisetin and Luteolin?
Both fisetin and luteolin are currently included in Essential Capsules.2
Lutein is also included in Advanced Antioxidants alongside zeaxanthin, astaxanthin, lycopene and vitamins K1 and K2.4
These compounds therefore remain part of Johnson's current supplement exposure even when they are no longer taken as separate products.
Does Bryan Johnson Take Peptides?
Yes, but this question requires an important distinction between daily products and separate experiments.
Topical Peptide Serum
Johnson's current public daily protocol includes Blueprint Peptide Serum as part of his scalp and hair routine. He applies 1 mL to his scalp in the morning and also uses skin and hair serums later in the day.1
Collagen Peptides
His daily nutrition routine also includes collagen peptides. These are dietary protein peptides and should not be confused with injectable research peptides or prescription peptide-based drugs.
CJC-1295 Experiment
In 2026, Johnson publicly documented a separate experiment with CJC-1295 DAC. He reported trying it for approximately two weeks while measuring changes in biomarkers and physiological responses.7
Johnson also reported adverse effects during the experiment, including disrupted sleep. He presented CJC-1295 as an experiment rather than part of his normal daily supplement stack.7
Tirzepatide Experiment
Johnson also previously experimented with microdosing tirzepatide, a prescription GLP-1/GIP receptor agonist. This was an earlier experiment beginning in late 2024 rather than a current 2026 daily supplement.
He reported stopping the experiment in January 2025 after approximately three weeks because his resting heart rate increased, heart-rate variability declined and his sleep quality worsened.8
So the most accurate summary is:
- Topical peptide serum: part of his current daily protocol.
- Collagen peptides: part of his current nutrition routine.
- CJC-1295: documented 2026 experiment, not a standard daily supplement.
- Tirzepatide: earlier experimental intervention that Johnson reported discontinuing.
What Prescription Medications Does Bryan Johnson Take?
Johnson publishes prescription medications separately from his supplements, and the two should not be treated as the same category.
There is also an important inconsistency within Johnson's current protocol page. His daily-routine section lists acarbose at 200 mg, while the separate prescription section lists 400 mg daily.1
Rather than choosing one value, the table below reflects what the current source actually says.
| Medication | Current Published Protocol |
|---|---|
| Armour Thyroid | 60 mg daily |
| Levothyroxine | 100 mcg daily |
| Oral minoxidil | 3.75 mg daily |
| Metformin | 500 mg; Johnson's daily routine says he is experimenting with six-week cycles on and off |
| Tadalafil | 5 mg daily |
| Jardiance | 10 mg daily |
| Candesartan | 8 mg daily in the separate Rx section |
| Acarbose | 200 mg in the daily routine; 400 mg daily in the separate Rx section |
| Repatha | 140 mg every other week |
These are prescription medications, not dietary supplements for readers to reproduce.
The fact that a medication appears in Johnson's personal protocol does not establish that it is appropriate for otherwise healthy people seeking longevity benefits.
Does Bryan Johnson Take Testosterone?
Testosterone is not listed in Johnson's current published supplement or prescription stack.1
That does not establish what he may or may not have experimented with historically. It only describes what appears in his current publicly documented protocol.
How Many Supplements Does Bryan Johnson Take Per Day?
There is no longer a particularly useful single number.
Johnson became widely known for taking a very large number of pills every day, but his current protocol uses several combination products containing numerous active ingredients.
For example, Essential Capsules contain 23 listed longevity actives, while Longevity Mix combines multiple amino acids, minerals and other compounds into a single scoop.23
That means:
The number of pills Bryan Johnson takes is not the same as the number of active ingredients in his protocol.
Claims that he currently takes "100 different supplements every day" can therefore be misleading when they are based on older versions of Blueprint.
Why Do Bryan Johnson Supplement Lists Differ?
The simplest reason is that his protocol changes.
Johnson continuously publishes updates to his diet, supplements, medications, exercise, sleep routine and experimental interventions. Blueprint has also developed combination products that contain ingredients he previously used separately.
Examples include:
- NR now appearing inside Essential Capsules
- Fisetin, luteolin, glucoraphanin and spermidine appearing in Essential Capsules
- Creatine appearing in Longevity Mix while also being supplemented separately
- Vitamin K1, vitamin K2, lycopene, astaxanthin, lutein and zeaxanthin being grouped in Advanced Antioxidants
- Ashwagandha and rhodiola being combined into one product
For that reason, first-party information from Johnson's current protocol is more useful for answering "What does Bryan Johnson take now?" than older screenshots or third-party supplement lists.
How Does Bryan Johnson Measure His Protocol?
Measurement is a central part of Johnson's approach.
His current Don't Die protocol recommends routine blood testing every 3 to 6 months and also lists periodic body imaging, dental visits, eye exams, glucose monitoring and other measurements.1
Johnson also describes changing or stopping interventions when his measurements suggest that an experiment is not producing the intended effect. His CJC-1295 and tirzepatide experiments are examples of this broader measure-and-adjust approach.
This context is important because simply copying a list of compounds removes one of the defining features of Johnson's protocol: ongoing measurement.
Are Bryan Johnson's Blueprint Supplements Third-Party Tested?
Blueprint states that products such as Essential Capsules and Advanced Antioxidants undergo third-party testing for factors including purity and heavy metals, and the company publishes Certificates of Analysis for a number of its products.26
That helps address questions about product manufacturing and testing.
It does not establish that Johnson's complete protocol has been clinically proven to extend human lifespan.
Those are separate questions:
- Product testing asks whether a product meets specifications for identity, purity or contaminants.
- Ingredient evidence asks what research exists for an individual compound or nutrient.
- Clinical effectiveness asks whether an intervention produces a demonstrated health outcome in humans.
- Protocol effectiveness would require evidence evaluating Johnson's overall combination of diet, supplements, exercise, medication and other interventions.
Those levels of evidence should not be treated as interchangeable.
Should You Copy Bryan Johnson's Supplement Stack?
Johnson's routine is built around his own medical history, laboratory results, biomarkers, diet, exercise habits and response to previous interventions.
It also includes prescription medications and experimental interventions.
For those reasons, his stack should primarily be viewed as a record of what Bryan Johnson currently does, rather than as a universal protocol.
A more useful aspect of his approach is the process behind it: identify a reason for an intervention, measure relevant outcomes, compare the result with the objective, and change course when the data does not support continuing.
The fact that Johnson takes an ingredient does not by itself establish that another person needs it, that the same dose is appropriate, or that it improves lifespan.
Bryan Johnson Supplements: The Bottom Line
Bryan Johnson still follows an extensive longevity routine in 2026, but his supplement stack is considerably more consolidated than many older lists suggest.
- Current core supplements: Longevity Mix, Essential Capsules, Advanced Antioxidants, Ashwagandha + Rhodiola, EPA/DHA, creatine and collagen peptides are all present in his published routine.
- NMN: separate oral NMN is not listed in his current supplement schedule. Essential Capsules contain NR instead.
- Creatine: Johnson currently states a total of 7.5 g from Longevity Mix plus additional creatine.
- Spermidine, fisetin and luteolin: these are incorporated into combination Blueprint products rather than necessarily being taken separately.
- Peptides: his current routine includes topical peptide serum and collagen peptides; CJC-1295 was a separate 2026 experiment.
- Prescription drugs: Johnson publishes these separately and they should not be treated as dietary supplements.
- Measurement: regular biomarker testing is a central part of how Johnson evaluates and changes his protocol.
Because the protocol changes over time, any Bryan Johnson supplement list should be dated and checked against his latest first-party protocol rather than copied from an older version.
Frequently Asked Questions
What supplements does Bryan Johnson currently take?
His current published routine includes Blueprint Longevity Mix, Essential Capsules, Advanced Antioxidants, Ashwagandha + Rhodiola, EPA/DHA, additional creatine, collagen peptides and several prebiotic fibers.1
Does Bryan Johnson take NAD+?
His current Essential Capsules contain nicotinamide riboside (NR), a precursor used to support NAD+ levels. Separate oral NMN is not listed in his current daily supplement schedule.2
Does Bryan Johnson still take NMN?
Separate NMN is not listed in his current 2026 supplement routine. Older descriptions of his protocol may list NMN or alternating NMN and NR, which is one reason historical supplement lists differ from his current published regimen.
Does Bryan Johnson take ashwagandha?
Yes. His current morning protocol lists one Ashwagandha + Rhodiola capsule.1
Does Bryan Johnson take creatine?
Yes. Johnson's current protocol lists 5 g of additional creatine along with approximately 2.5 g in Longevity Mix, for a stated total of 7.5 g.1
Does Bryan Johnson take peptides?
His current daily routine includes topical Peptide Serum and collagen peptides. He also documented a separate CJC-1295 experiment in 2026, but that should not be confused with his standard daily supplement stack.17
What pills does Bryan Johnson take every day?
His morning protocol currently lists two Essential Capsules, one Advanced Antioxidants capsule and one Ashwagandha + Rhodiola capsule alongside other powders, fibers and nutritional products.1
Does Bryan Johnson take testosterone?
Testosterone is not listed in the current supplement or prescription medication stack on Johnson's published protocol page.1
How often does Bryan Johnson get blood tests?
His current protocol lists a routine blood draw every 3 to 6 months as part of his biomarker-monitoring program.1
References
- Johnson B. Bryan Johnson's Don't Die Protocol. Accessed September 2026.
- Blueprint. Essential Capsules. Product formulation and directions. Accessed September 2026.
- Blueprint. Longevity Mix – Blood Orange. Product formulation and directions. Accessed September 2026.
- Blueprint. Advanced Antioxidants. Product formulation and directions. Accessed September 2026.
- Blueprint. Ashwagandha + Rhodiola. Product formulation and directions. Accessed September 2026.
- Blueprint. Certificates of Analysis. Accessed September 2026.
- Johnson B. CJC-1295 peptide experiment. May 2026.
- Johnson B. Tirzepatide microdosing experiment and discontinuation. January 2025.